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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP8B2 All Species: 23.94
Human Site: S1115 Identified Species: 52.67
UniProt: P98198 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P98198 NP_001005855.1 1209 137440 S1115 L N L K P D L S D T V R Y T Q
Chimpanzee Pan troglodytes XP_001151835 1209 137422 S1115 L N L K P D L S D T V R Y T Q
Rhesus Macaque Macaca mulatta XP_001114367 1203 136654 K1111 R F L R L N L K P D L S D T V
Dog Lupus familis XP_547569 1209 136878 S1115 L S L K P D L S D T V R Y T Q
Cat Felis silvestris
Mouse Mus musculus P98199 1209 136949 S1115 L S L K P D L S D T V R Y T Q
Rat Rattus norvegicus XP_002726040 1209 136925 S1115 L S L K P D L S D T V R Y T Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_429208 1172 133646 V1083 I A L C V L P V V G F R F L K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_687715 1223 139712 T1126 T D L Y P T H T D K V R L L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396773 1378 155607 S1277 I D V R P T L S D R V R L K Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LNQ4 1216 138171 L1129 L V T V T T V L P Y F A H I S
Baker's Yeast Sacchar. cerevisiae P39524 1355 153826 I1260 V Q Q F Q N A I R K V R Q V Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 100 99 95.2 N.A. 97 97.2 N.A. N.A. 65.1 N.A. 70.6 N.A. N.A. 50.4 N.A. N.A.
Protein Similarity: 100 100 99.2 98 N.A. 98.9 99 N.A. N.A. 77.5 N.A. 82.9 N.A. N.A. 64.8 N.A. N.A.
P-Site Identity: 100 100 20 93.3 N.A. 93.3 93.3 N.A. N.A. 13.3 N.A. 40 N.A. N.A. 46.6 N.A. N.A.
P-Site Similarity: 100 100 40 100 N.A. 100 100 N.A. N.A. 33.3 N.A. 53.3 N.A. N.A. 73.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 39.8 35.5 N.A.
Protein Similarity: N.A. N.A. N.A. 59.4 54.3 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 10 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 19 0 0 0 46 0 0 64 10 0 0 10 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 10 0 10 0 0 0 0 0 0 19 0 10 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % H
% Ile: 19 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % I
% Lys: 0 0 0 46 0 0 0 10 0 19 0 0 0 10 10 % K
% Leu: 55 0 73 0 10 10 64 10 0 0 10 0 19 19 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 19 0 0 0 19 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 64 0 10 0 19 0 0 0 0 0 0 % P
% Gln: 0 10 10 0 10 0 0 0 0 0 0 0 10 0 73 % Q
% Arg: 10 0 0 19 0 0 0 0 10 10 0 82 0 0 0 % R
% Ser: 0 28 0 0 0 0 0 55 0 0 0 10 0 0 10 % S
% Thr: 10 0 10 0 10 28 0 10 0 46 0 0 0 55 0 % T
% Val: 10 10 10 10 10 0 10 10 10 0 73 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 10 0 0 46 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _