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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP8B2 All Species: 22.73
Human Site: S1187 Identified Species: 50
UniProt: P98198 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P98198 NP_001005855.1 1209 137440 S1187 S S S S W I E S L R R K K S D
Chimpanzee Pan troglodytes XP_001151835 1209 137422 S1187 S S S S W I E S L R R K K S D
Rhesus Macaque Macaca mulatta XP_001114367 1203 136654 S1181 S S S S W I E S L R R K K S D
Dog Lupus familis XP_547569 1209 136878 S1187 S S S N W I E S L R R K K S D
Cat Felis silvestris
Mouse Mus musculus P98199 1209 136949 S1187 S S S S W I E S L R R K K S D
Rat Rattus norvegicus XP_002726040 1209 136925 S1187 S S S S W I E S L R R K K S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_429208 1172 133646 P1150 M S G R N M R P K S P F A T T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_687715 1223 139712 E1198 S P S R A P G E K G T T S A N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396773 1378 155607 K1353 P F T N N T S K Q V N V A T T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LNQ4 1216 138171 N1196 R H L R S K L N K K Q S N M S
Baker's Yeast Sacchar. cerevisiae P39524 1355 153826 N1332 S A E P F I E N P F A D G N Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 100 99 95.2 N.A. 97 97.2 N.A. N.A. 65.1 N.A. 70.6 N.A. N.A. 50.4 N.A. N.A.
Protein Similarity: 100 100 99.2 98 N.A. 98.9 99 N.A. N.A. 77.5 N.A. 82.9 N.A. N.A. 64.8 N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 100 100 N.A. N.A. 6.6 N.A. 13.3 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 20 N.A. 26.6 N.A. N.A. 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 39.8 35.5 N.A.
Protein Similarity: N.A. N.A. N.A. 59.4 54.3 N.A.
P-Site Identity: N.A. N.A. N.A. 0 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 10 0 0 0 0 0 10 0 19 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 55 % D
% Glu: 0 0 10 0 0 0 64 10 0 0 0 0 0 0 0 % E
% Phe: 0 10 0 0 10 0 0 0 0 10 0 10 0 0 0 % F
% Gly: 0 0 10 0 0 0 10 0 0 10 0 0 10 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 64 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 10 28 10 0 55 55 0 0 % K
% Leu: 0 0 10 0 0 0 10 0 55 0 0 0 0 0 0 % L
% Met: 10 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 19 19 0 0 19 0 0 10 0 10 10 10 % N
% Pro: 10 10 0 10 0 10 0 10 10 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 10 % Q
% Arg: 10 0 0 28 0 0 10 0 0 55 55 0 0 0 0 % R
% Ser: 73 64 64 46 10 0 10 55 0 10 0 10 10 55 10 % S
% Thr: 0 0 10 0 0 10 0 0 0 0 10 10 0 19 19 % T
% Val: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % V
% Trp: 0 0 0 0 55 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _