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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP8B2
All Species:
22.12
Human Site:
S757
Identified Species:
48.67
UniProt:
P98198
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P98198
NP_001005855.1
1209
137440
S757
F
T
Y
Q
D
K
L
S
S
S
K
L
T
S
V
Chimpanzee
Pan troglodytes
XP_001151835
1209
137422
S757
F
T
Y
Q
D
K
L
S
S
S
K
L
T
S
V
Rhesus Macaque
Macaca mulatta
XP_001114367
1203
136654
S757
F
T
Y
Q
E
K
L
S
S
S
K
L
T
S
V
Dog
Lupus familis
XP_547569
1209
136878
S757
F
T
C
Q
E
R
R
S
S
A
K
L
T
S
V
Cat
Felis silvestris
Mouse
Mus musculus
P98199
1209
136949
S757
F
T
Y
Q
G
N
L
S
S
S
K
L
T
S
V
Rat
Rattus norvegicus
XP_002726040
1209
136925
S757
F
T
Y
Q
G
N
L
S
S
S
K
L
T
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_429208
1172
133646
S740
N
I
Q
I
E
K
S
S
K
N
L
K
L
L
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687715
1223
139712
L768
L
D
M
E
K
T
E
L
Y
S
V
D
S
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396773
1378
155607
E926
V
T
F
R
W
D
K
E
R
D
E
Q
D
E
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LNQ4
1216
138171
K791
N
I
L
N
Q
I
T
K
A
V
Q
M
V
K
L
Baker's Yeast
Sacchar. cerevisiae
P39524
1355
153826
D898
K
S
L
A
L
V
I
D
G
K
S
L
G
F
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
99
95.2
N.A.
97
97.2
N.A.
N.A.
65.1
N.A.
70.6
N.A.
N.A.
50.4
N.A.
N.A.
Protein Similarity:
100
100
99.2
98
N.A.
98.9
99
N.A.
N.A.
77.5
N.A.
82.9
N.A.
N.A.
64.8
N.A.
N.A.
P-Site Identity:
100
100
93.3
66.6
N.A.
86.6
86.6
N.A.
N.A.
13.3
N.A.
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
26.6
N.A.
20
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.8
35.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.4
54.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
10
10
0
0
0
0
10
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
19
10
0
10
0
10
0
10
10
0
0
% D
% Glu:
0
0
0
10
28
0
10
10
0
0
10
0
0
10
0
% E
% Phe:
55
0
10
0
0
0
0
0
0
0
0
0
0
10
10
% F
% Gly:
0
0
0
0
19
0
0
0
10
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
19
0
10
0
10
10
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
10
37
10
10
10
10
55
10
0
10
0
% K
% Leu:
10
0
19
0
10
0
46
10
0
0
10
64
10
10
10
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
19
0
0
10
0
19
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
10
55
10
0
0
0
0
0
10
10
0
0
0
% Q
% Arg:
0
0
0
10
0
10
10
0
10
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
0
0
10
64
55
55
10
0
10
55
0
% S
% Thr:
0
64
0
0
0
10
10
0
0
0
0
0
55
0
0
% T
% Val:
10
0
0
0
0
10
0
0
0
10
10
0
10
10
55
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
46
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _