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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP8B2
All Species:
30
Human Site:
Y374
Identified Species:
66
UniProt:
P98198
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P98198
NP_001005855.1
1209
137440
Y374
V
I
R
L
G
H
S
Y
F
I
N
W
D
K
K
Chimpanzee
Pan troglodytes
XP_001151835
1209
137422
Y374
V
I
R
L
G
H
S
Y
F
I
N
W
D
K
K
Rhesus Macaque
Macaca mulatta
XP_001114367
1203
136654
Y374
V
I
R
L
G
H
S
Y
F
I
N
W
D
K
K
Dog
Lupus familis
XP_547569
1209
136878
Y374
V
I
R
L
G
H
S
Y
F
I
N
W
D
K
K
Cat
Felis silvestris
Mouse
Mus musculus
P98199
1209
136949
Y374
V
I
R
L
G
H
S
Y
F
I
N
W
D
K
K
Rat
Rattus norvegicus
XP_002726040
1209
136925
Y374
V
I
R
L
G
H
S
Y
F
I
N
W
D
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_429208
1172
133646
F356
I
I
R
L
G
N
S
F
Y
I
D
W
D
R
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687715
1223
139712
Y384
V
L
R
L
G
H
S
Y
F
I
N
W
D
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396773
1378
155607
F540
V
I
R
F
V
Q
S
F
L
I
N
W
D
E
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LNQ4
1216
138171
S388
V
V
K
V
L
Q
A
S
F
I
N
K
D
L
H
Baker's Yeast
Sacchar. cerevisiae
P39524
1355
153826
F523
L
I
K
Y
Y
Q
A
F
M
I
G
S
D
L
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
99
95.2
N.A.
97
97.2
N.A.
N.A.
65.1
N.A.
70.6
N.A.
N.A.
50.4
N.A.
N.A.
Protein Similarity:
100
100
99.2
98
N.A.
98.9
99
N.A.
N.A.
77.5
N.A.
82.9
N.A.
N.A.
64.8
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
60
N.A.
80
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
73.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.8
35.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.4
54.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
100
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% E
% Phe:
0
0
0
10
0
0
0
28
73
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
73
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
64
0
0
0
0
0
0
0
0
10
% H
% Ile:
10
82
0
0
0
0
0
0
0
100
0
0
0
0
0
% I
% Lys:
0
0
19
0
0
0
0
0
0
0
0
10
0
55
64
% K
% Leu:
10
10
0
73
10
0
0
0
10
0
0
0
0
19
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
82
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
28
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
82
0
0
0
0
0
0
0
0
0
0
19
10
% R
% Ser:
0
0
0
0
0
0
82
10
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
82
10
0
10
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
82
0
0
0
% W
% Tyr:
0
0
0
10
10
0
0
64
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _