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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R2B
All Species:
31.52
Human Site:
S382
Identified Species:
63.03
UniProt:
Q00005
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00005
NP_001120853.1
443
51710
S382
L
E
A
S
R
E
N
S
K
P
R
A
I
L
K
Chimpanzee
Pan troglodytes
XP_001159292
427
49658
P374
K
P
R
A
I
L
K
P
R
K
V
C
V
G
G
Rhesus Macaque
Macaca mulatta
XP_001091436
453
51968
S392
L
E
A
S
R
E
S
S
K
P
R
A
S
L
K
Dog
Lupus familis
XP_535231
443
51664
S382
L
E
A
S
R
E
N
S
K
P
R
A
I
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG02
447
51443
S382
L
E
A
S
R
E
S
S
K
P
R
A
V
L
K
Rat
Rattus norvegicus
P36877
443
51650
S382
L
E
A
S
R
E
N
S
K
P
R
A
I
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIY5
451
51997
S390
L
E
A
S
R
E
S
S
K
P
R
A
I
L
K
Frog
Xenopus laevis
A1L3L9
468
54505
S407
L
E
A
S
R
E
N
S
K
P
R
A
I
L
K
Zebra Danio
Brachydanio rerio
NP_001025293
443
51566
S382
L
E
A
S
R
E
N
S
K
P
R
A
I
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P36872
499
56948
I439
L
E
A
S
R
D
I
I
K
P
K
T
V
L
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39247
501
56256
N431
A
T
L
E
A
S
K
N
P
M
R
R
Q
I
Q
Baker's Yeast
Sacchar. cerevisiae
Q00362
526
59644
F393
D
N
G
I
V
K
T
F
D
E
H
N
A
P
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
82.3
99.5
N.A.
85.6
99.5
N.A.
N.A.
83.5
88.2
93.2
N.A.
69.3
N.A.
N.A.
N.A.
Protein Similarity:
100
95.7
90.9
100
N.A.
94.8
99.7
N.A.
N.A.
91.5
91.4
97.9
N.A.
78.9
N.A.
N.A.
N.A.
P-Site Identity:
100
0
86.6
100
N.A.
86.6
100
N.A.
N.A.
93.3
100
100
N.A.
60
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
93.3
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
80
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
50.3
47.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
64.8
63.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
75
9
9
0
0
0
0
0
0
67
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
9
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% D
% Glu:
0
75
0
9
0
67
0
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
9
9
0
9
9
0
0
0
0
50
9
0
% I
% Lys:
9
0
0
0
0
9
17
0
75
9
9
0
0
0
75
% K
% Leu:
75
0
9
0
0
9
0
0
0
0
0
0
0
75
0
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
42
9
0
0
0
9
0
0
9
% N
% Pro:
0
9
0
0
0
0
0
9
9
75
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% Q
% Arg:
0
0
9
0
75
0
0
0
9
0
75
9
0
0
0
% R
% Ser:
0
0
0
75
0
9
25
67
0
0
0
0
9
0
0
% S
% Thr:
0
9
0
0
0
0
9
0
0
0
0
9
0
0
0
% T
% Val:
0
0
0
0
9
0
0
0
0
0
9
0
25
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _