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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R2B
All Species:
17.88
Human Site:
Y185
Identified Species:
35.76
UniProt:
Q00005
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00005
NP_001120853.1
443
51710
Y185
S
I
S
V
N
S
D
Y
E
T
Y
M
S
A
D
Chimpanzee
Pan troglodytes
XP_001159292
427
49658
L178
T
Y
M
S
A
D
D
L
R
I
N
L
W
N
F
Rhesus Macaque
Macaca mulatta
XP_001091436
453
51968
H195
S
I
S
V
N
S
D
H
E
T
Y
L
S
A
D
Dog
Lupus familis
XP_535231
443
51664
Y185
S
I
S
V
N
S
D
Y
E
T
Y
M
S
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG02
447
51443
C185
S
I
S
V
N
S
D
C
E
T
Y
M
S
A
D
Rat
Rattus norvegicus
P36877
443
51650
Y185
S
I
S
V
N
S
D
Y
E
T
Y
M
S
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIY5
451
51997
H193
S
I
S
V
N
S
D
H
E
T
Y
L
S
A
D
Frog
Xenopus laevis
A1L3L9
468
54505
Y210
S
I
S
V
N
S
D
Y
E
T
Y
M
S
A
D
Zebra Danio
Brachydanio rerio
NP_001025293
443
51566
Y185
S
I
S
V
N
S
D
Y
E
T
Y
M
S
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P36872
499
56948
Q242
S
I
S
V
N
S
D
Q
E
T
F
L
S
A
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39247
501
56256
G234
S
I
S
N
S
S
D
G
E
T
F
I
S
A
D
Baker's Yeast
Sacchar. cerevisiae
Q00362
526
59644
Q196
S
I
S
L
N
S
D
Q
E
T
F
L
S
A
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
82.3
99.5
N.A.
85.6
99.5
N.A.
N.A.
83.5
88.2
93.2
N.A.
69.3
N.A.
N.A.
N.A.
Protein Similarity:
100
95.7
90.9
100
N.A.
94.8
99.7
N.A.
N.A.
91.5
91.4
97.9
N.A.
78.9
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
86.6
100
N.A.
93.3
100
N.A.
N.A.
86.6
100
93.3
N.A.
80
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
93.3
100
N.A.
N.A.
100
100
93.3
N.A.
93.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
50.3
47.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
64.8
63.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
73.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
0
0
0
0
84
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
100
0
0
0
0
0
0
0
92
% D
% Glu:
0
0
0
0
0
0
0
0
92
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
9
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% H
% Ile:
0
92
0
0
0
0
0
0
0
9
0
9
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
9
0
0
0
9
0
0
0
42
0
0
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
50
0
0
0
% M
% Asn:
0
0
0
9
84
0
0
0
0
0
9
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% R
% Ser:
92
0
92
9
9
92
0
0
0
0
0
0
92
0
0
% S
% Thr:
9
0
0
0
0
0
0
0
0
92
0
0
0
9
0
% T
% Val:
0
0
0
75
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
9
0
0
0
0
0
42
0
0
67
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _