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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP1
All Species:
26.97
Human Site:
Y251
Identified Species:
49.44
UniProt:
Q00013
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00013
NP_002427.1
466
52296
Y251
P
F
G
K
K
K
K
Y
K
D
K
Y
L
A
K
Chimpanzee
Pan troglodytes
XP_001143670
466
52277
Y251
P
F
G
K
K
K
K
Y
K
D
K
Y
L
A
K
Rhesus Macaque
Macaca mulatta
XP_001097559
469
52568
Y251
P
F
G
K
K
K
K
Y
K
D
K
Y
L
A
K
Dog
Lupus familis
XP_855454
544
60389
Y329
P
F
G
K
K
K
K
Y
K
D
K
Y
L
A
K
Cat
Felis silvestris
Mouse
Mus musculus
P70290
466
52209
C251
P
F
G
K
K
K
K
C
K
D
K
Y
L
A
K
Rat
Rattus norvegicus
Q62915
909
103240
K691
A
S
C
T
W
F
G
K
K
K
K
Q
Y
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513222
468
52731
Y253
P
F
G
K
K
K
K
Y
K
D
K
Y
L
A
K
Chicken
Gallus gallus
Q5ZJ00
468
52501
Y253
P
F
G
K
K
K
K
Y
K
D
K
Y
L
A
K
Frog
Xenopus laevis
NP_001079689
460
51420
C246
P
F
S
K
K
K
K
C
K
D
K
Y
L
A
K
Zebra Danio
Brachydanio rerio
Q6P0D7
576
65174
M337
D
K
K
T
N
K
S
M
Y
E
C
K
K
S
E
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
C252
P
F
G
K
K
K
K
C
K
D
K
Y
L
A
K
Fruit Fly
Dros. melanogaster
Q24210
898
100893
Y680
K
K
Q
C
R
D
K
Y
L
A
K
H
N
A
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P54936
961
108794
Y743
F
N
K
K
K
K
Y
Y
T
T
K
Y
L
Q
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.4
80.3
N.A.
92.9
32.8
N.A.
85.9
83.1
66.7
32.2
63.3
30.7
N.A.
26.9
N.A.
Protein Similarity:
100
100
98.2
82.9
N.A.
95
42.9
N.A.
92.7
92.5
80.6
49.4
77.7
41.2
N.A.
37.3
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
13.3
N.A.
100
100
86.6
6.6
93.3
26.6
N.A.
53.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
13.3
N.A.
100
100
86.6
26.6
93.3
40
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
8
0
0
0
77
0
% A
% Cys:
0
0
8
8
0
0
0
24
0
0
8
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
0
0
0
70
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% E
% Phe:
8
70
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
62
0
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
8
16
16
77
77
85
77
8
77
8
93
8
8
8
77
% K
% Leu:
0
0
0
0
0
0
0
0
8
0
0
0
77
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
70
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
8
0
8
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
8
0
0
0
8
0
0
0
0
0
0
8
0
% S
% Thr:
0
0
0
16
0
0
0
0
8
8
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
62
8
0
0
77
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _