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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TFAM
All Species:
12.73
Human Site:
S124
Identified Species:
25.45
UniProt:
Q00059
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00059
NP_003192.1
246
29097
S124
F
K
E
Q
L
T
P
S
Q
I
M
S
L
E
K
Chimpanzee
Pan troglodytes
XP_001163932
230
26804
E112
A
E
W
Q
V
Y
K
E
E
I
S
R
F
K
E
Rhesus Macaque
Macaca mulatta
XP_001097656
248
29455
D124
F
K
E
Q
L
T
P
D
E
I
T
S
L
E
K
Dog
Lupus familis
XP_546107
246
28817
S124
I
Q
E
Q
L
T
P
S
Q
I
M
S
L
E
K
Cat
Felis silvestris
Mouse
Mus musculus
P40630
243
27969
S123
Y
K
E
Q
L
T
P
S
Q
L
M
G
M
E
K
Rat
Rattus norvegicus
Q91ZW1
244
28168
S123
Y
K
E
Q
L
T
P
S
Q
L
M
G
L
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507921
336
37980
F200
Y
K
E
E
L
A
K
F
K
A
T
S
V
P
L
Chicken
Gallus gallus
NP_989431
262
29968
A133
E
E
R
R
K
R
L
A
K
R
R
S
F
R
I
Frog
Xenopus laevis
NP_001081106
309
35482
V155
Y
R
E
A
L
S
P
V
Q
L
E
L
H
R
E
Zebra Danio
Brachydanio rerio
NP_001070857
277
31508
E122
K
A
Q
L
T
P
A
E
S
A
A
F
A
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q06943
111
12638
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_194111
456
53213
M212
E
K
R
E
K
E
A
M
K
L
L
E
D
D
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.7
85.8
71.5
N.A.
61.3
62.2
N.A.
35.7
41.9
36.5
37.1
N.A.
21.9
N.A.
N.A.
N.A.
Protein Similarity:
100
85.7
95.5
85.3
N.A.
77.2
77.2
N.A.
50.5
63.7
54.6
55.9
N.A.
32.1
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
80
86.6
N.A.
73.3
80
N.A.
26.6
6.6
26.6
6.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
86.6
93.3
N.A.
93.3
93.3
N.A.
53.3
33.3
60
20
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
31.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
9
0
9
17
9
0
17
9
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
0
0
9
9
0
% D
% Glu:
17
17
59
17
0
9
0
17
17
0
9
9
0
50
25
% E
% Phe:
17
0
0
0
0
0
0
9
0
0
0
9
17
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
34
0
0
0
0
9
% I
% Lys:
9
50
0
0
17
0
17
0
25
0
0
0
0
9
42
% K
% Leu:
0
0
0
9
59
0
9
0
0
34
9
9
34
0
9
% L
% Met:
0
0
0
0
0
0
0
9
0
0
34
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
9
50
0
0
0
0
0
0
9
0
% P
% Gln:
0
9
9
50
0
0
0
0
42
0
0
0
0
0
9
% Q
% Arg:
0
9
17
9
0
9
0
0
0
9
9
9
0
17
0
% R
% Ser:
0
0
0
0
0
9
0
34
9
0
9
42
0
0
0
% S
% Thr:
0
0
0
0
9
42
0
0
0
0
17
0
0
0
0
% T
% Val:
0
0
0
0
9
0
0
9
0
0
0
0
9
0
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
34
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _