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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TFAM
All Species:
13.03
Human Site:
T234
Identified Species:
26.06
UniProt:
Q00059
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00059
NP_003192.1
246
29097
T234
R
K
D
L
L
R
R
T
I
K
K
Q
R
K
Y
Chimpanzee
Pan troglodytes
XP_001163932
230
26804
R219
I
S
V
R
E
Y
I
R
A
R
L
D
S
C
E
Rhesus Macaque
Macaca mulatta
XP_001097656
248
29455
T234
R
K
D
V
L
R
R
T
I
K
Q
R
Q
K
Y
Dog
Lupus familis
XP_546107
246
28817
S234
R
N
D
L
L
R
R
S
V
K
H
Q
G
K
D
Cat
Felis silvestris
Mouse
Mus musculus
P40630
243
27969
R232
G
R
S
D
L
I
R
R
S
V
K
R
S
G
D
Rat
Rattus norvegicus
Q91ZW1
244
28168
S233
R
S
D
L
I
R
R
S
V
K
R
P
P
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507921
336
37980
K314
R
E
D
L
L
R
S
K
S
R
R
R
K
T
E
Chicken
Gallus gallus
NP_989431
262
29968
S251
S
K
A
S
L
R
E
S
L
A
K
L
K
L
K
Frog
Xenopus laevis
NP_001081106
309
35482
N265
R
G
D
L
I
R
L
N
Q
R
K
R
F
K
K
Zebra Danio
Brachydanio rerio
NP_001070857
277
31508
K231
R
E
D
L
L
R
R
K
T
K
S
A
L
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q06943
111
12638
E100
A
K
K
A
K
K
K
E
S
S
E
E
E
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_194111
456
53213
A438
K
A
A
K
L
M
E
A
Y
K
K
E
V
E
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.7
85.8
71.5
N.A.
61.3
62.2
N.A.
35.7
41.9
36.5
37.1
N.A.
21.9
N.A.
N.A.
N.A.
Protein Similarity:
100
85.7
95.5
85.3
N.A.
77.2
77.2
N.A.
50.5
63.7
54.6
55.9
N.A.
32.1
N.A.
N.A.
N.A.
P-Site Identity:
100
0
73.3
60
N.A.
20
40
N.A.
33.3
26.6
40
53.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
73.3
N.A.
33.3
66.6
N.A.
66.6
46.6
60
60
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
31.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
17
9
0
0
0
9
9
9
0
9
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
59
9
0
0
0
0
0
0
0
9
0
0
25
% D
% Glu:
0
17
0
0
9
0
17
9
0
0
9
17
9
17
25
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
9
9
0
0
0
0
0
0
0
0
0
0
9
17
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
9
0
0
0
17
9
9
0
17
0
0
0
0
0
0
% I
% Lys:
9
34
9
9
9
9
9
17
0
50
42
0
17
42
17
% K
% Leu:
0
0
0
50
67
0
9
0
9
0
9
9
9
9
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
9
17
9
0
0
% Q
% Arg:
59
9
0
9
0
67
50
17
0
25
17
34
9
0
0
% R
% Ser:
9
17
9
9
0
0
9
25
25
9
9
0
17
0
0
% S
% Thr:
0
0
0
0
0
0
0
17
9
0
0
0
0
9
0
% T
% Val:
0
0
9
9
0
0
0
0
17
9
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _