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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TFAM
All Species:
13.03
Human Site:
Y165
Identified Species:
26.06
UniProt:
Q00059
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00059
NP_003192.1
246
29097
Y165
P
R
S
A
Y
N
V
Y
V
A
E
R
F
Q
E
Chimpanzee
Pan troglodytes
XP_001163932
230
26804
L152
K
K
K
E
L
T
L
L
G
K
P
K
R
P
R
Rhesus Macaque
Macaca mulatta
XP_001097656
248
29455
Y165
P
R
S
A
Y
N
V
Y
V
A
E
R
F
Q
E
Dog
Lupus familis
XP_546107
246
28817
F165
P
R
S
A
Y
N
I
F
I
A
E
R
F
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
P40630
243
27969
Y164
P
R
S
A
Y
N
I
Y
V
S
E
S
F
Q
E
Rat
Rattus norvegicus
Q91ZW1
244
28168
Y164
P
R
S
A
Y
N
I
Y
V
S
E
S
F
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507921
336
37980
F245
P
H
S
A
Y
N
I
F
V
V
E
R
L
Q
E
Chicken
Gallus gallus
NP_989431
262
29968
K176
K
G
L
S
P
T
A
K
L
K
Q
L
F
E
T
Frog
Xenopus laevis
NP_001081106
309
35482
F196
P
R
S
P
F
N
I
F
M
S
E
H
F
Q
D
Zebra Danio
Brachydanio rerio
NP_001070857
277
31508
F162
P
R
S
T
F
N
I
F
M
A
E
H
F
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q06943
111
12638
V33
K
D
N
P
G
S
K
V
T
D
I
A
K
R
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_194111
456
53213
A316
N
K
E
T
Y
L
Q
A
M
E
E
Y
K
R
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.7
85.8
71.5
N.A.
61.3
62.2
N.A.
35.7
41.9
36.5
37.1
N.A.
21.9
N.A.
N.A.
N.A.
Protein Similarity:
100
85.7
95.5
85.3
N.A.
77.2
77.2
N.A.
50.5
63.7
54.6
55.9
N.A.
32.1
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
80
N.A.
80
80
N.A.
66.6
6.6
46.6
53.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
93.3
93.3
N.A.
80
33.3
86.6
80
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
31.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
50
0
0
9
9
0
34
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
9
% D
% Glu:
0
0
9
9
0
0
0
0
0
9
75
0
0
9
59
% E
% Phe:
0
0
0
0
17
0
0
34
0
0
0
0
67
0
0
% F
% Gly:
0
9
0
0
9
0
0
0
9
0
0
0
0
0
9
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
17
0
0
0
% H
% Ile:
0
0
0
0
0
0
50
0
9
0
9
0
0
0
0
% I
% Lys:
25
17
9
0
0
0
9
9
0
17
0
9
17
0
0
% K
% Leu:
0
0
9
0
9
9
9
9
9
0
0
9
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% M
% Asn:
9
0
9
0
0
67
0
0
0
0
0
0
0
0
0
% N
% Pro:
67
0
0
17
9
0
0
0
0
0
9
0
0
9
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
9
0
0
59
0
% Q
% Arg:
0
59
0
0
0
0
0
0
0
0
0
34
9
17
9
% R
% Ser:
0
0
67
9
0
9
0
0
0
25
0
17
0
0
0
% S
% Thr:
0
0
0
17
0
17
0
0
9
0
0
0
0
0
17
% T
% Val:
0
0
0
0
0
0
17
9
42
9
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
59
0
0
34
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _