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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A3
All Species:
43.64
Human Site:
S298
Identified Species:
64
UniProt:
Q00325
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00325
NP_002626.1
362
40095
S298
L
N
K
E
K
G
S
S
A
S
L
V
L
K
R
Chimpanzee
Pan troglodytes
XP_509289
315
34683
Q261
S
E
C
S
K
P
E
Q
L
V
V
T
F
V
A
Rhesus Macaque
Macaca mulatta
XP_001083690
362
40156
S298
L
N
K
E
K
G
S
S
A
S
Q
V
L
K
R
Dog
Lupus familis
XP_866402
362
39917
S298
L
N
K
E
K
G
S
S
A
S
Q
V
L
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEM8
357
39614
T293
L
N
K
E
K
G
S
T
A
S
Q
V
L
Q
R
Rat
Rattus norvegicus
P16036
356
39427
T292
L
N
K
E
K
G
S
T
A
S
Q
V
L
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506076
369
41102
S305
L
N
K
E
K
G
S
S
A
S
Q
V
L
Q
R
Chicken
Gallus gallus
NP_001006236
335
37403
F281
Q
V
L
K
R
L
G
F
R
G
V
W
K
G
L
Frog
Xenopus laevis
NP_001080195
359
39888
T295
L
N
K
E
K
G
S
T
A
V
E
V
L
K
R
Zebra Danio
Brachydanio rerio
NP_998887
356
39288
T292
L
N
K
E
K
G
S
T
A
G
Q
V
L
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611468
374
40535
S308
L
N
Q
A
K
G
A
S
A
L
D
V
A
K
Q
Honey Bee
Apis mellifera
XP_396960
354
39111
S291
L
N
Q
E
K
G
A
S
A
I
D
V
L
R
K
Nematode Worm
Caenorhab. elegans
P40614
340
36655
G285
G
G
I
L
K
K
L
G
F
A
G
V
W
K
G
Sea Urchin
Strong. purpuratus
XP_783048
356
39100
T295
L
N
Q
D
S
G
S
T
A
I
E
A
A
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001140930
356
39513
T292
L
N
K
E
K
G
S
T
A
S
Q
V
L
Q
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40035
300
33510
N246
I
N
S
E
R
K
A
N
E
S
M
S
V
A
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.4
98.3
95.3
N.A.
88.6
88.1
N.A.
81.3
79
82.8
79.5
N.A.
67.3
67.1
65.4
69.3
Protein Similarity:
100
85.9
99.4
96.1
N.A.
93.9
93.6
N.A.
87.2
84.2
90
87
N.A.
79.9
79.5
75.6
81.2
P-Site Identity:
100
6.6
93.3
86.6
N.A.
80
80
N.A.
86.6
0
80
80
N.A.
53.3
60
20
40
P-Site Similarity:
100
13.3
93.3
93.3
N.A.
93.3
93.3
N.A.
93.3
20
86.6
86.6
N.A.
73.3
86.6
26.6
66.6
Percent
Protein Identity:
N.A.
88.6
N.A.
N.A.
41.9
N.A.
Protein Similarity:
N.A.
93.9
N.A.
N.A.
56.9
N.A.
P-Site Identity:
N.A.
80
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
93.3
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
19
0
75
7
0
7
13
7
7
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
0
0
0
0
13
0
0
0
0
% D
% Glu:
0
7
0
69
0
0
7
0
7
0
13
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
7
7
0
0
0
7
0
0
% F
% Gly:
7
7
0
0
0
75
7
7
0
13
7
0
0
7
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
7
0
0
0
0
0
0
13
0
0
0
0
0
% I
% Lys:
0
0
57
7
82
13
0
0
0
0
0
0
7
44
13
% K
% Leu:
75
0
7
7
0
7
7
0
7
7
7
0
63
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
82
0
0
0
0
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
19
0
0
0
0
7
0
0
44
0
0
32
7
% Q
% Arg:
0
0
0
0
13
0
0
0
7
0
0
0
0
7
57
% R
% Ser:
7
0
7
7
7
0
63
38
0
50
0
7
0
0
7
% S
% Thr:
0
0
0
0
0
0
0
38
0
0
0
7
0
0
0
% T
% Val:
0
7
0
0
0
0
0
0
0
13
13
75
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _