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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A3
All Species:
47.27
Human Site:
Y141
Identified Species:
69.33
UniProt:
Q00325
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00325
NP_002626.1
362
40095
Y141
G
L
C
K
F
G
F
Y
E
V
F
K
V
L
Y
Chimpanzee
Pan troglodytes
XP_509289
315
34683
L110
F
N
G
F
S
V
T
L
K
E
D
G
V
R
G
Rhesus Macaque
Macaca mulatta
XP_001083690
362
40156
Y141
G
L
C
K
F
G
F
Y
E
V
F
K
V
L
Y
Dog
Lupus familis
XP_866402
362
39917
Y141
G
L
C
K
F
G
F
Y
E
V
F
K
V
L
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEM8
357
39614
Y136
G
L
C
K
F
G
F
Y
E
V
F
K
A
L
Y
Rat
Rattus norvegicus
P16036
356
39427
Y135
G
L
C
K
F
G
F
Y
E
V
F
K
A
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506076
369
41102
Y148
G
L
C
K
F
G
F
Y
E
V
F
K
V
L
Y
Chicken
Gallus gallus
NP_001006236
335
37403
A130
N
M
L
G
E
E
N
A
Y
L
W
R
T
S
L
Frog
Xenopus laevis
NP_001080195
359
39888
Y138
G
L
C
K
F
G
F
Y
E
V
F
K
I
L
Y
Zebra Danio
Brachydanio rerio
NP_998887
356
39288
Y135
G
L
C
K
F
G
F
Y
E
V
F
K
I
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611468
374
40535
Y151
G
L
C
K
F
G
L
Y
E
V
F
K
K
V
Y
Honey Bee
Apis mellifera
XP_396960
354
39111
Y134
G
M
F
K
F
G
L
Y
E
I
F
K
V
Y
Y
Nematode Worm
Caenorhab. elegans
P40614
340
36655
N134
A
D
M
L
G
E
E
N
A
Y
L
Y
R
T
S
Sea Urchin
Strong. purpuratus
XP_783048
356
39100
Y138
G
L
C
K
F
G
F
Y
E
V
F
K
N
V
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001140930
356
39513
Y135
G
L
C
K
F
G
F
Y
E
V
F
K
A
L
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40035
300
33510
E95
A
G
K
Y
G
G
Y
E
Y
F
K
H
L
Y
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.4
98.3
95.3
N.A.
88.6
88.1
N.A.
81.3
79
82.8
79.5
N.A.
67.3
67.1
65.4
69.3
Protein Similarity:
100
85.9
99.4
96.1
N.A.
93.9
93.6
N.A.
87.2
84.2
90
87
N.A.
79.9
79.5
75.6
81.2
P-Site Identity:
100
6.6
100
100
N.A.
93.3
93.3
N.A.
100
0
93.3
93.3
N.A.
80
66.6
0
86.6
P-Site Similarity:
100
13.3
100
100
N.A.
93.3
93.3
N.A.
100
26.6
100
100
N.A.
86.6
80
0
93.3
Percent
Protein Identity:
N.A.
88.6
N.A.
N.A.
41.9
N.A.
Protein Similarity:
N.A.
93.9
N.A.
N.A.
56.9
N.A.
P-Site Identity:
N.A.
93.3
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
93.3
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
0
0
0
7
7
0
0
0
19
0
0
% A
% Cys:
0
0
69
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
0
% D
% Glu:
0
0
0
0
7
13
7
7
75
7
0
0
0
0
0
% E
% Phe:
7
0
7
7
75
0
63
0
0
7
75
0
0
0
0
% F
% Gly:
75
7
7
7
13
82
0
0
0
0
0
7
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
7
0
0
13
0
0
% I
% Lys:
0
0
7
75
0
0
0
0
7
0
7
75
7
0
0
% K
% Leu:
0
69
7
7
0
0
13
7
0
7
7
0
7
57
7
% L
% Met:
0
13
7
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
7
0
0
0
0
7
7
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
7
7
7
0
% R
% Ser:
0
0
0
0
7
0
0
0
0
0
0
0
0
7
13
% S
% Thr:
0
0
0
0
0
0
7
0
0
0
0
0
7
7
0
% T
% Val:
0
0
0
0
0
7
0
0
0
69
0
0
38
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
7
75
13
7
0
7
0
13
75
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _