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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A3
All Species:
40.61
Human Site:
Y158
Identified Species:
59.56
UniProt:
Q00325
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00325
NP_002626.1
362
40095
Y158
M
L
G
E
E
N
T
Y
L
W
R
T
S
L
Y
Chimpanzee
Pan troglodytes
XP_509289
315
34683
L127
K
G
W
A
P
T
F
L
G
Y
S
M
Q
G
L
Rhesus Macaque
Macaca mulatta
XP_001083690
362
40156
Y158
M
L
G
E
E
N
T
Y
L
W
R
T
S
L
Y
Dog
Lupus familis
XP_866402
362
39917
Y158
M
L
G
E
E
N
A
Y
L
W
R
T
S
L
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEM8
357
39614
Y153
I
L
G
E
E
N
T
Y
L
W
R
T
S
L
Y
Rat
Rattus norvegicus
P16036
356
39427
Y152
I
L
G
E
E
N
T
Y
L
W
R
T
S
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506076
369
41102
Y165
I
L
G
E
E
N
T
Y
L
W
R
T
S
L
Y
Chicken
Gallus gallus
NP_001006236
335
37403
F147
A
A
S
A
S
A
E
F
F
A
D
I
A
L
A
Frog
Xenopus laevis
NP_001080195
359
39888
Y155
M
M
G
E
E
N
T
Y
L
W
R
T
S
L
Y
Zebra Danio
Brachydanio rerio
NP_998887
356
39288
Y152
M
L
G
E
E
N
A
Y
M
W
R
T
S
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611468
374
40535
F168
A
I
G
E
E
N
A
F
L
Y
R
T
G
L
Y
Honey Bee
Apis mellifera
XP_396960
354
39111
Y151
L
A
G
E
E
M
A
Y
E
F
R
T
S
L
Y
Nematode Worm
Caenorhab. elegans
P40614
340
36655
E151
L
A
A
S
A
S
A
E
F
F
A
D
I
L
L
Sea Urchin
Strong. purpuratus
XP_783048
356
39100
F155
L
L
G
E
E
R
A
F
L
Y
R
T
S
L
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001140930
356
39513
Y152
I
L
G
E
E
N
T
Y
L
W
R
T
S
L
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40035
300
33510
Y112
L
S
P
G
V
T
V
Y
L
M
A
S
A
T
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.4
98.3
95.3
N.A.
88.6
88.1
N.A.
81.3
79
82.8
79.5
N.A.
67.3
67.1
65.4
69.3
Protein Similarity:
100
85.9
99.4
96.1
N.A.
93.9
93.6
N.A.
87.2
84.2
90
87
N.A.
79.9
79.5
75.6
81.2
P-Site Identity:
100
0
100
93.3
N.A.
93.3
93.3
N.A.
93.3
6.6
93.3
86.6
N.A.
60
60
6.6
66.6
P-Site Similarity:
100
6.6
100
93.3
N.A.
100
100
N.A.
100
20
100
93.3
N.A.
80
73.3
26.6
86.6
Percent
Protein Identity:
N.A.
88.6
N.A.
N.A.
41.9
N.A.
Protein Similarity:
N.A.
93.9
N.A.
N.A.
56.9
N.A.
P-Site Identity:
N.A.
93.3
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
100
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
19
7
13
7
7
38
0
0
7
13
0
13
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% D
% Glu:
0
0
0
75
75
0
7
7
7
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
7
19
13
13
0
0
0
0
0
% F
% Gly:
0
7
75
7
0
0
0
0
7
0
0
0
7
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
25
7
0
0
0
0
0
0
0
0
0
7
7
0
0
% I
% Lys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
25
57
0
0
0
0
0
7
69
0
0
0
0
88
13
% L
% Met:
32
7
0
0
0
7
0
0
7
7
0
7
0
0
0
% M
% Asn:
0
0
0
0
0
63
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
0
0
0
0
0
7
0
0
0
0
75
0
0
0
0
% R
% Ser:
0
7
7
7
7
7
0
0
0
0
7
7
69
0
0
% S
% Thr:
0
0
0
0
0
13
44
0
0
0
0
75
0
7
0
% T
% Val:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
57
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
69
0
19
0
0
0
0
75
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _