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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A3
All Species:
17.58
Human Site:
Y59
Identified Species:
25.78
UniProt:
Q00325
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00325
NP_002626.1
362
40095
Y59
E
E
Q
Y
S
C
D
Y
G
S
G
R
F
F
I
Chimpanzee
Pan troglodytes
XP_509289
315
34683
S33
L
G
D
L
R
S
S
S
P
G
P
T
G
Q
P
Rhesus Macaque
Macaca mulatta
XP_001083690
362
40156
Y59
E
E
Q
Y
S
C
D
Y
G
S
G
R
F
F
I
Dog
Lupus familis
XP_866402
362
39917
Y59
E
E
Q
Y
S
C
D
Y
G
S
G
R
F
F
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEM8
357
39614
S56
E
Y
S
C
E
F
G
S
M
K
Y
Y
A
L
C
Rat
Rattus norvegicus
P16036
356
39427
M56
Y
S
C
E
F
G
S
M
K
Y
Y
A
L
C
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506076
369
41102
Y66
I
T
E
Y
S
C
E
Y
G
S
L
K
Y
Y
A
Chicken
Gallus gallus
NP_001006236
335
37403
C53
S
A
T
E
E
Y
S
C
E
Y
G
S
L
K
F
Frog
Xenopus laevis
NP_001080195
359
39888
Y56
D
D
E
F
S
C
E
Y
G
S
A
Q
F
Y
A
Zebra Danio
Brachydanio rerio
NP_998887
356
39288
K57
S
C
A
F
G
S
G
K
Y
Y
A
L
C
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611468
374
40535
F69
A
E
G
D
S
C
E
F
G
S
N
H
Y
F
L
Honey Bee
Apis mellifera
XP_396960
354
39111
K56
S
C
E
F
G
S
N
K
Y
F
M
L
C
G
L
Nematode Worm
Caenorhab. elegans
P40614
340
36655
I56
G
G
V
L
S
C
G
I
T
H
T
A
I
V
P
Sea Urchin
Strong. purpuratus
XP_783048
356
39100
F56
S
T
E
T
S
C
E
F
G
S
A
K
Y
Y
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001140930
356
39513
M56
Y
S
C
E
F
G
S
M
K
Y
Y
A
L
C
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40035
300
33510
Y18
Q
L
Y
T
K
E
F
Y
A
T
C
T
L
G
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.4
98.3
95.3
N.A.
88.6
88.1
N.A.
81.3
79
82.8
79.5
N.A.
67.3
67.1
65.4
69.3
Protein Similarity:
100
85.9
99.4
96.1
N.A.
93.9
93.6
N.A.
87.2
84.2
90
87
N.A.
79.9
79.5
75.6
81.2
P-Site Identity:
100
0
100
100
N.A.
6.6
0
N.A.
40
6.6
40
0
N.A.
40
0
13.3
26.6
P-Site Similarity:
100
0
100
100
N.A.
6.6
0
N.A.
73.3
6.6
86.6
6.6
N.A.
66.6
26.6
13.3
66.6
Percent
Protein Identity:
N.A.
88.6
N.A.
N.A.
41.9
N.A.
Protein Similarity:
N.A.
93.9
N.A.
N.A.
56.9
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
0
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
0
0
0
0
0
7
0
19
19
7
0
19
% A
% Cys:
0
13
13
7
0
50
0
7
0
0
7
0
13
13
7
% C
% Asp:
7
7
7
7
0
0
19
0
0
0
0
0
0
0
0
% D
% Glu:
25
25
25
19
13
7
25
0
7
0
0
0
0
0
0
% E
% Phe:
0
0
0
19
13
7
7
13
0
7
0
0
25
25
13
% F
% Gly:
7
13
7
0
13
13
19
0
44
7
25
0
7
19
19
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
7
0
0
0
0
7
0
19
% I
% Lys:
0
0
0
0
7
0
0
13
13
7
0
13
0
7
0
% K
% Leu:
7
7
0
13
0
0
0
0
0
0
7
13
25
7
13
% L
% Met:
0
0
0
0
0
0
0
13
7
0
7
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
7
0
0
0
13
% P
% Gln:
7
0
19
0
0
0
0
0
0
0
0
7
0
7
0
% Q
% Arg:
0
0
0
0
7
0
0
0
0
0
0
19
0
0
0
% R
% Ser:
25
13
7
0
50
19
25
13
0
44
0
7
0
0
0
% S
% Thr:
0
13
7
13
0
0
0
0
7
7
7
13
0
0
0
% T
% Val:
0
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
7
7
25
0
7
0
38
13
25
19
7
19
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _