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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2B
All Species:
52.42
Human Site:
S262
Identified Species:
82.38
UniProt:
Q00403
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00403
NP_001505.1
316
34833
S262
A
A
A
I
Y
M
A
S
Q
A
S
A
E
K
R
Chimpanzee
Pan troglodytes
XP_001147170
373
40961
S319
A
A
A
I
Y
M
A
S
Q
A
S
A
E
K
R
Rhesus Macaque
Macaca mulatta
XP_001083435
373
41048
S319
A
A
A
I
Y
M
A
S
Q
A
S
A
E
K
R
Dog
Lupus familis
XP_867247
273
29897
S220
D
F
M
S
R
F
C
S
N
L
C
L
P
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
P62916
316
34800
S262
A
A
A
I
Y
M
A
S
Q
A
S
A
E
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508212
544
59987
S396
A
A
A
I
Y
M
A
S
Q
A
S
T
E
K
R
Chicken
Gallus gallus
XP_422356
468
51101
S414
A
A
A
I
Y
M
A
S
Q
A
S
A
E
K
R
Frog
Xenopus laevis
P29054
316
34659
S262
A
A
A
I
Y
M
A
S
Q
A
S
A
E
K
R
Zebra Danio
Brachydanio rerio
NP_955991
316
34817
S262
A
A
A
I
Y
M
A
S
Q
A
S
A
E
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29052
315
34351
S261
A
A
A
I
Y
M
A
S
Q
A
S
E
H
K
R
Honey Bee
Apis mellifera
XP_395432
315
34279
S261
A
A
A
I
Y
M
A
S
Q
A
S
E
D
K
R
Nematode Worm
Caenorhab. elegans
O16991
306
33083
S252
A
A
A
I
Y
M
A
S
Q
A
S
A
E
K
R
Sea Urchin
Strong. purpuratus
XP_796335
321
34941
S267
A
A
A
I
Y
M
A
S
Q
A
S
E
E
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48512
312
34253
T258
A
V
V
I
Y
I
I
T
Q
L
S
D
D
K
K
Baker's Yeast
Sacchar. cerevisiae
P29055
345
38182
I286
V
V
S
I
Y
L
N
I
L
L
F
Q
I
P
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.7
84.7
86.3
N.A.
N.A.
99.6
N.A.
55.5
66
94.3
93.6
N.A.
79.1
81.3
60.1
71.9
Protein Similarity:
100
84.7
84.7
86.3
N.A.
N.A.
100
N.A.
56.6
66.6
97.4
97.4
N.A.
88.9
89.2
78.4
84.4
P-Site Identity:
100
100
100
13.3
N.A.
N.A.
100
N.A.
93.3
100
100
93.3
N.A.
86.6
86.6
100
93.3
P-Site Similarity:
100
100
100
20
N.A.
N.A.
100
N.A.
93.3
100
100
100
N.A.
86.6
93.3
100
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.5
33
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61.3
51
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
87
80
80
0
0
0
80
0
0
80
0
54
0
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
0
0
0
7
14
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
20
67
0
0
% E
% Phe:
0
7
0
0
0
7
0
0
0
0
7
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
94
0
7
7
7
0
0
0
0
7
0
7
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
94
14
% K
% Leu:
0
0
0
0
0
7
0
0
7
20
0
7
0
0
0
% L
% Met:
0
0
7
0
0
80
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
0
7
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% P
% Gln:
0
0
0
0
0
0
0
0
87
0
0
7
0
0
7
% Q
% Arg:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
74
% R
% Ser:
0
0
7
7
0
0
0
87
0
0
87
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% T
% Val:
7
14
7
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
94
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _