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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GTF2B All Species: 32.5
Human Site: S5 Identified Species: 51.07
UniProt: Q00403 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q00403 NP_001505.1 316 34833 S5 _ _ _ M A S T S R L D A L P R
Chimpanzee Pan troglodytes XP_001147170 373 40961 S62 A V K M A S T S R L D A L P R
Rhesus Macaque Macaca mulatta XP_001083435 373 41048 S62 A L K M A S T S R L D A L P R
Dog Lupus familis XP_867247 273 29897
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus P62916 316 34800 S5 _ _ _ M A S T S R L D A L P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508212 544 59987 A110 T M S S S D R A I M N A F K E
Chicken Gallus gallus XP_422356 468 51101 S157 G S E M A S T S R L D A L P R
Frog Xenopus laevis P29054 316 34659 S5 _ _ _ M A S T S R I D A L P K
Zebra Danio Brachydanio rerio NP_955991 316 34817 S5 _ _ _ M A S T S R G D S L P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P29052 315 34351 S5 _ _ _ M A S T S R L D N N K V
Honey Bee Apis mellifera XP_395432 315 34279 S5 _ _ _ M A S S S R H E T N K V
Nematode Worm Caenorhab. elegans O16991 306 33083 V5 _ _ _ M S A P V Q C P I H P D
Sea Urchin Strong. purpuratus XP_796335 321 34941 S10 S T S K G S A S A S A P M H K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P48512 312 34253 Y5 _ _ _ M S D A Y C T D C K K E
Baker's Yeast Sacchar. cerevisiae P29055 345 38182 P16 K R A G R R G P N L N I V L T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.7 84.7 86.3 N.A. N.A. 99.6 N.A. 55.5 66 94.3 93.6 N.A. 79.1 81.3 60.1 71.9
Protein Similarity: 100 84.7 84.7 86.3 N.A. N.A. 100 N.A. 56.6 66.6 97.4 97.4 N.A. 88.9 89.2 78.4 84.4
P-Site Identity: 100 80 80 0 N.A. N.A. 100 N.A. 6.6 80 83.3 75 N.A. 66.6 41.6 16.6 13.3
P-Site Similarity: 100 80 80 0 N.A. N.A. 100 N.A. 33.3 86.6 100 91.6 N.A. 66.6 58.3 41.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. 45.5 33 N.A.
Protein Similarity: N.A. N.A. N.A. 61.3 51 N.A.
P-Site Identity: N.A. N.A. N.A. 16.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 25 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 7 0 60 7 14 7 7 0 7 47 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 7 7 0 7 0 0 0 % C
% Asp: 0 0 0 0 0 14 0 0 0 0 60 0 0 0 7 % D
% Glu: 0 0 7 0 0 0 0 0 0 0 7 0 0 0 14 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % F
% Gly: 7 0 0 7 7 0 7 0 0 7 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 7 0 0 7 7 0 % H
% Ile: 0 0 0 0 0 0 0 0 7 7 0 14 0 0 0 % I
% Lys: 7 0 14 7 0 0 0 0 0 0 0 0 7 27 20 % K
% Leu: 0 7 0 0 0 0 0 0 0 47 0 0 47 7 0 % L
% Met: 0 7 0 74 0 0 0 0 0 7 0 0 7 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 7 0 14 7 14 0 0 % N
% Pro: 0 0 0 0 0 0 7 7 0 0 7 7 0 54 0 % P
% Gln: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % Q
% Arg: 0 7 0 0 7 7 7 0 60 0 0 0 0 0 34 % R
% Ser: 7 7 14 7 20 67 7 67 0 7 0 7 0 0 0 % S
% Thr: 7 7 0 0 0 0 54 0 0 7 0 7 0 0 7 % T
% Val: 0 7 0 0 0 0 0 7 0 0 0 0 7 0 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % Y
% Spaces: 54 54 54 0 0 0 0 0 0 0 0 0 0 0 0 % _