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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2B
All Species:
55.15
Human Site:
Y289
Identified Species:
86.67
UniProt:
Q00403
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00403
NP_001505.1
316
34833
Y289
D
V
T
I
R
Q
S
Y
R
L
I
Y
P
R
A
Chimpanzee
Pan troglodytes
XP_001147170
373
40961
Y346
D
V
T
I
R
Q
S
Y
R
L
I
Y
P
R
A
Rhesus Macaque
Macaca mulatta
XP_001083435
373
41048
Y346
D
V
T
I
R
Q
S
Y
R
L
I
Y
P
R
A
Dog
Lupus familis
XP_867247
273
29897
G247
V
E
L
D
L
V
P
G
R
S
P
I
S
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
P62916
316
34800
Y289
D
V
T
I
R
Q
S
Y
R
L
I
Y
P
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508212
544
59987
Y517
D
V
T
I
R
Q
S
Y
R
L
I
Y
P
R
A
Chicken
Gallus gallus
XP_422356
468
51101
Y441
D
V
T
I
R
Q
S
Y
R
L
I
Y
P
R
A
Frog
Xenopus laevis
P29054
316
34659
Y289
D
V
T
I
R
Q
S
Y
R
L
I
Y
P
R
A
Zebra Danio
Brachydanio rerio
NP_955991
316
34817
Y289
D
V
T
I
R
Q
S
Y
R
L
I
Y
P
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29052
315
34351
Y288
D
V
T
I
R
Q
S
Y
K
L
M
Y
P
H
A
Honey Bee
Apis mellifera
XP_395432
315
34279
Y288
D
V
T
I
R
Q
S
Y
K
L
M
Y
P
H
A
Nematode Worm
Caenorhab. elegans
O16991
306
33083
Y279
E
I
T
V
R
Q
T
Y
K
L
L
Y
P
K
A
Sea Urchin
Strong. purpuratus
XP_796335
321
34941
Y294
D
V
T
I
R
Q
S
Y
K
L
I
Y
P
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48512
312
34253
Y285
E
G
T
I
R
N
S
Y
K
D
L
Y
P
H
L
Baker's Yeast
Sacchar. cerevisiae
P29055
345
38182
Y313
E
G
T
I
K
S
G
Y
K
I
L
Y
E
H
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.7
84.7
86.3
N.A.
N.A.
99.6
N.A.
55.5
66
94.3
93.6
N.A.
79.1
81.3
60.1
71.9
Protein Similarity:
100
84.7
84.7
86.3
N.A.
N.A.
100
N.A.
56.6
66.6
97.4
97.4
N.A.
88.9
89.2
78.4
84.4
P-Site Identity:
100
100
100
13.3
N.A.
N.A.
100
N.A.
100
100
100
100
N.A.
80
80
53.3
80
P-Site Similarity:
100
100
100
13.3
N.A.
N.A.
100
N.A.
100
100
100
100
N.A.
93.3
93.3
100
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.5
33
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61.3
51
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
80
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
74
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% D
% Glu:
20
7
0
0
0
0
0
0
0
0
0
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
14
0
0
0
0
7
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
27
0
% H
% Ile:
0
7
0
87
0
0
0
0
0
7
60
7
0
0
0
% I
% Lys:
0
0
0
0
7
0
0
0
40
0
0
0
0
14
0
% K
% Leu:
0
0
7
0
7
0
0
0
0
80
20
0
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
14
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
7
0
0
0
7
0
87
0
0
% P
% Gln:
0
0
0
0
0
80
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
87
0
0
0
60
0
0
0
0
54
7
% R
% Ser:
0
0
0
0
0
7
80
0
0
7
0
0
7
0
7
% S
% Thr:
0
0
94
0
0
0
7
0
0
0
0
0
0
0
0
% T
% Val:
7
74
0
7
0
7
0
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
94
0
0
0
94
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _