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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK3 All Species: 66.97
Human Site: Y19 Identified Species: 92.08
UniProt: Q00526 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q00526 NP_001249.1 305 35046 Y19 E G T Y G V V Y K A K N R E T
Chimpanzee Pan troglodytes XP_523720 325 36841 Y39 E G T Y G V V Y K A K N R E T
Rhesus Macaque Macaca mulatta XP_001102596 305 34903 Y19 E G T Y G V V Y K A K N R E T
Dog Lupus familis XP_540442 303 34173 Y19 E G T Y G V V Y K A K N K E T
Cat Felis silvestris
Mouse Mus musculus Q80YP0 303 33870 Y19 E G T Y G V V Y K A R N K V T
Rat Rattus norvegicus Q63699 298 33869 Y19 E G T Y G V V Y K A K N K L T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P13863 303 34670 Y19 E G T Y G V V Y K G R H K T T
Frog Xenopus laevis P23437 297 33852 Y19 E G T Y G V V Y K A R N R E T
Zebra Danio Brachydanio rerio NP_998571 298 34001 Y19 E G T Y G V V Y K A K N K V T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P23572 297 34420 Y19 E G T Y G V V Y K G R N R L T
Honey Bee Apis mellifera XP_393450 299 34033 Y19 E G T Y G V V Y K A K D K L T
Nematode Worm Caenorhab. elegans P34556 332 38277 Y37 E G T Y G V V Y K G K N R R T
Sea Urchin Strong. purpuratus XP_790847 299 34142 Y19 E G T Y G V V Y K A R D L K S
Poplar Tree Populus trichocarpa XP_002306004 294 33768 Y19 E G T Y G V V Y K A R D R V T
Maize Zea mays P23111 294 33816 Y19 E G T Y G V V Y K A L D K A T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P24100 294 34012 Y19 E G T Y G V V Y K A R D K V T
Baker's Yeast Sacchar. cerevisiae P00546 298 34043 Y23 E G T Y G V V Y K A L D L R P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.5 96.7 88.5 N.A. 82.6 74.7 N.A. N.A. 63.6 73.7 73.7 N.A. 62.9 67.2 58.1 69.5
Protein Similarity: 100 93.5 98.3 92.7 N.A. 91.8 84.5 N.A. N.A. 78 84.5 83.2 N.A. 76.7 80.6 69.5 82.6
P-Site Identity: 100 100 100 93.3 N.A. 80 86.6 N.A. N.A. 66.6 93.3 86.6 N.A. 80 80 86.6 66.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 86.6 100 93.3 N.A. 86.6 93.3 86.6 93.3
Percent
Protein Identity: 65.2 64.2 N.A. 65.5 62.3 N.A.
Protein Similarity: 81.6 80.9 N.A. 81.3 77.7 N.A.
P-Site Identity: 80 73.3 N.A. 73.3 66.6 N.A.
P-Site Similarity: 93.3 86.6 N.A. 93.3 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 83 0 0 0 6 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 36 0 0 0 % D
% Glu: 100 0 0 0 0 0 0 0 0 0 0 0 0 30 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 100 0 0 100 0 0 0 0 18 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 100 0 48 0 48 6 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 12 0 12 18 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 59 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 42 0 42 12 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % S
% Thr: 0 0 100 0 0 0 0 0 0 0 0 0 0 6 89 % T
% Val: 0 0 0 0 0 100 100 0 0 0 0 0 0 24 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 100 0 0 0 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _