Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK16 All Species: 27.27
Human Site: S479 Identified Species: 50
UniProt: Q00536 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q00536 NP_006192.1 496 55716 S479 K E A S L R S S S M P D S G R
Chimpanzee Pan troglodytes XP_521035 762 83144 S745 K E A S L R S S S M P D S G R
Rhesus Macaque Macaca mulatta XP_001100911 485 54881 S468 K E A S L R S S S M P D S G R
Dog Lupus familis XP_538015 500 56072 S483 K E A S L R S S S M P D S G R
Cat Felis silvestris
Mouse Mus musculus Q04735 496 55895 T479 K E A N I R S T S M P D S G R
Rat Rattus norvegicus Q63686 496 55746 T479 K E A N I R S T S M P D S G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521338 549 61821 A532 K E M G L R S A S L P D S G R
Chicken Gallus gallus XP_416161 516 58803 S486 R I H S L P E S V S I F S L K
Frog Xenopus laevis Q6DJM7 435 49211 V419 E A G E S M R V F G K N N S F
Zebra Danio Brachydanio rerio Q1RLU9 418 47889 S402 S E A R D I F S P S R R T K T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48609 294 33162 A277 R P N Q R I S A E A A M Q H P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P23111 294 33816 T277 Y E P S K R I T A R Q A L E H
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P24100 294 34012 N277 M D P T K R I N A R A A L E H
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 58 89.3 97.5 N.A. 97.5 95.5 N.A. 76.1 69.1 45.1 41.9 N.A. 35.4 N.A. N.A. N.A.
Protein Similarity: 100 60.8 90.3 98 N.A. 98.9 97.3 N.A. 81 82.9 59.6 55.8 N.A. 43.9 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 80 80 N.A. 73.3 26.6 0 20 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 86.6 40 20 26.6 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 33 N.A. 33.4 N.A. N.A.
Protein Similarity: N.A. 45.3 N.A. 46.3 N.A. N.A.
P-Site Identity: N.A. 20 N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. 33.3 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 54 0 0 0 0 16 16 8 16 16 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 8 0 0 0 0 0 0 54 0 0 0 % D
% Glu: 8 70 0 8 0 0 8 0 8 0 0 0 0 16 0 % E
% Phe: 0 0 0 0 0 0 8 0 8 0 0 8 0 0 8 % F
% Gly: 0 0 8 8 0 0 0 0 0 8 0 0 0 54 0 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 16 % H
% Ile: 0 8 0 0 16 16 16 0 0 0 8 0 0 0 0 % I
% Lys: 54 0 0 0 16 0 0 0 0 0 8 0 0 8 8 % K
% Leu: 0 0 0 0 47 0 0 0 0 8 0 0 16 8 0 % L
% Met: 8 0 8 0 0 8 0 0 0 47 0 8 0 0 0 % M
% Asn: 0 0 8 16 0 0 0 8 0 0 0 8 8 0 0 % N
% Pro: 0 8 16 0 0 8 0 0 8 0 54 0 0 0 8 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 8 0 8 0 0 % Q
% Arg: 16 0 0 8 8 70 8 0 0 16 8 8 0 0 54 % R
% Ser: 8 0 0 47 8 0 62 47 54 16 0 0 62 8 0 % S
% Thr: 0 0 0 8 0 0 0 24 0 0 0 0 8 0 8 % T
% Val: 0 0 0 0 0 0 0 8 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _