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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK16 All Species: 26.36
Human Site: S480 Identified Species: 48.33
UniProt: Q00536 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q00536 NP_006192.1 496 55716 S480 E A S L R S S S M P D S G R P
Chimpanzee Pan troglodytes XP_521035 762 83144 S746 E A S L R S S S M P D S G R P
Rhesus Macaque Macaca mulatta XP_001100911 485 54881 S469 E A S L R S S S M P D S G R P
Dog Lupus familis XP_538015 500 56072 S484 E A S L R S S S M P D S G R P
Cat Felis silvestris
Mouse Mus musculus Q04735 496 55895 S480 E A N I R S T S M P D S G R P
Rat Rattus norvegicus Q63686 496 55746 S480 E A N I R S T S M P D S G R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521338 549 61821 S533 E M G L R S A S L P D S G R S
Chicken Gallus gallus XP_416161 516 58803 V487 I H S L P E S V S I F S L K E
Frog Xenopus laevis Q6DJM7 435 49211 F420 A G E S M R V F G K N N S F S
Zebra Danio Brachydanio rerio Q1RLU9 418 47889 P403 E A R D I F S P S R R T K T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48609 294 33162 E278 P N Q R I S A E A A M Q H P Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P23111 294 33816 A278 E P S K R I T A R Q A L E H E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P24100 294 34012 A278 D P T K R I N A R A A L E H E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 58 89.3 97.5 N.A. 97.5 95.5 N.A. 76.1 69.1 45.1 41.9 N.A. 35.4 N.A. N.A. N.A.
Protein Similarity: 100 60.8 90.3 98 N.A. 98.9 97.3 N.A. 81 82.9 59.6 55.8 N.A. 43.9 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 80 80 N.A. 66.6 26.6 0 26.6 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 80 33.3 13.3 33.3 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 33 N.A. 33.4 N.A. N.A.
Protein Similarity: N.A. 45.3 N.A. 46.3 N.A. N.A.
P-Site Identity: N.A. 20 N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. 33.3 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 54 0 0 0 0 16 16 8 16 16 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 8 0 0 0 0 0 0 54 0 0 0 0 % D
% Glu: 70 0 8 0 0 8 0 8 0 0 0 0 16 0 24 % E
% Phe: 0 0 0 0 0 8 0 8 0 0 8 0 0 8 0 % F
% Gly: 0 8 8 0 0 0 0 0 8 0 0 0 54 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 8 16 0 % H
% Ile: 8 0 0 16 16 16 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 0 0 16 0 0 0 0 0 8 0 0 8 8 0 % K
% Leu: 0 0 0 47 0 0 0 0 8 0 0 16 8 0 0 % L
% Met: 0 8 0 0 8 0 0 0 47 0 8 0 0 0 0 % M
% Asn: 0 8 16 0 0 0 8 0 0 0 8 8 0 0 0 % N
% Pro: 8 16 0 0 8 0 0 8 0 54 0 0 0 8 54 % P
% Gln: 0 0 8 0 0 0 0 0 0 8 0 8 0 0 0 % Q
% Arg: 0 0 8 8 70 8 0 0 16 8 8 0 0 54 0 % R
% Ser: 0 0 47 8 0 62 47 54 16 0 0 62 8 0 16 % S
% Thr: 0 0 8 0 0 0 24 0 0 0 0 8 0 8 0 % T
% Val: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _