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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK16
All Species:
31.82
Human Site:
T459
Identified Species:
58.33
UniProt:
Q00536
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00536
NP_006192.1
496
55716
T459
R
I
H
K
L
P
D
T
T
S
I
F
A
L
K
Chimpanzee
Pan troglodytes
XP_521035
762
83144
T725
R
I
H
K
L
P
D
T
T
S
I
F
A
L
K
Rhesus Macaque
Macaca mulatta
XP_001100911
485
54881
T448
R
I
H
K
L
P
D
T
T
S
I
F
A
L
K
Dog
Lupus familis
XP_538015
500
56072
T463
R
I
H
K
L
P
D
T
T
S
I
F
A
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q04735
496
55895
T459
R
I
H
K
L
P
D
T
T
S
I
F
A
L
K
Rat
Rattus norvegicus
Q63686
496
55746
T459
R
I
H
K
L
P
D
T
T
S
I
F
A
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521338
549
61821
T512
R
V
L
K
L
P
D
T
T
S
I
F
A
L
K
Chicken
Gallus gallus
XP_416161
516
58803
E466
K
K
R
I
S
A
E
E
A
M
K
H
A
Y
F
Frog
Xenopus laevis
Q6DJM7
435
49211
S399
L
W
E
L
S
D
M
S
S
I
F
T
V
P
N
Zebra Danio
Brachydanio rerio
Q1RLU9
418
47889
T382
P
L
M
H
L
R
D
T
V
S
I
F
K
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48609
294
33162
S257
Q
L
V
P
R
L
N
S
K
G
R
D
L
L
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
D257
A
T
V
V
P
N
L
D
P
A
G
L
D
L
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
D257
E
T
F
V
P
N
L
D
P
D
G
V
D
L
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58
89.3
97.5
N.A.
97.5
95.5
N.A.
76.1
69.1
45.1
41.9
N.A.
35.4
N.A.
N.A.
N.A.
Protein Similarity:
100
60.8
90.3
98
N.A.
98.9
97.3
N.A.
81
82.9
59.6
55.8
N.A.
43.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
86.6
6.6
0
40
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
20
13.3
53.3
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
33
N.A.
33.4
N.A.
N.A.
Protein Similarity:
N.A.
45.3
N.A.
46.3
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
0
8
8
0
0
62
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
62
16
0
8
0
8
16
0
0
% D
% Glu:
8
0
8
0
0
0
8
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
8
62
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
16
0
0
0
0
% G
% His:
0
0
47
8
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
47
0
8
0
0
0
0
0
8
62
0
0
0
0
% I
% Lys:
8
8
0
54
0
0
0
0
8
0
8
0
8
0
54
% K
% Leu:
8
16
8
8
62
8
16
0
0
0
0
8
8
77
16
% L
% Met:
0
0
8
0
0
0
8
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
16
8
0
0
0
0
0
0
0
8
% N
% Pro:
8
0
0
8
16
54
0
0
16
0
0
0
0
8
8
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
54
0
8
0
8
8
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
16
0
0
16
8
62
0
0
0
0
0
% S
% Thr:
0
16
0
0
0
0
0
62
54
0
0
8
0
0
0
% T
% Val:
0
8
16
16
0
0
0
0
8
0
0
8
8
8
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _