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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PURA
All Species:
23.94
Human Site:
T225
Identified Species:
52.67
UniProt:
Q00577
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00577
NP_005850.1
322
34911
T225
L
P
E
G
T
S
L
T
V
D
N
K
R
F
F
Chimpanzee
Pan troglodytes
XP_001136727
295
32969
Y213
F
D
V
G
S
N
K
Y
G
V
F
M
R
V
S
Rhesus Macaque
Macaca mulatta
XP_001085737
322
34991
T225
L
P
E
G
T
S
L
T
V
D
N
K
R
F
F
Dog
Lupus familis
XP_544287
404
42773
T307
L
P
E
G
T
S
L
T
V
D
N
K
R
F
F
Cat
Felis silvestris
Mouse
Mus musculus
P42669
321
34865
T224
L
P
E
G
T
S
L
T
V
D
N
K
R
F
F
Rat
Rattus norvegicus
Q68A21
315
33399
T229
L
P
E
G
T
S
I
T
V
D
S
K
R
F
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426295
336
38538
R257
L
P
E
G
T
S
F
R
V
D
N
K
R
F
Y
Frog
Xenopus laevis
Q8AVS4
328
34968
T232
L
P
E
G
T
S
I
T
V
D
S
K
R
F
F
Zebra Danio
Brachydanio rerio
Q6PHK6
297
32588
M218
L
P
E
G
T
S
I
M
V
D
S
K
R
F
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726579
274
30978
H198
G
D
L
P
E
E
R
H
M
K
V
D
N
K
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784262
259
29404
E183
E
G
Q
G
N
V
P
E
S
K
S
F
R
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.3
99.6
79.6
N.A.
99.3
69.5
N.A.
N.A.
50.5
67.3
67.6
N.A.
41.2
N.A.
N.A.
46.5
Protein Similarity:
100
91.3
99.6
79.6
N.A.
99.3
77.9
N.A.
N.A.
64.2
75.3
76.7
N.A.
58.7
N.A.
N.A.
59.9
P-Site Identity:
100
13.3
100
100
N.A.
100
86.6
N.A.
N.A.
80
86.6
80
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
N.A.
86.6
100
93.3
N.A.
6.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
0
0
0
0
0
0
0
73
0
10
0
0
0
% D
% Glu:
10
0
73
0
10
10
0
10
0
0
0
0
0
0
10
% E
% Phe:
10
0
0
0
0
0
10
0
0
0
10
10
0
73
64
% F
% Gly:
10
10
0
91
0
0
0
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
28
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
19
0
73
0
10
0
% K
% Leu:
73
0
10
0
0
0
37
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
10
10
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
10
10
0
0
0
0
46
0
10
0
10
% N
% Pro:
0
73
0
10
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
10
0
0
0
0
91
0
0
% R
% Ser:
0
0
0
0
10
73
0
0
10
0
37
0
0
0
10
% S
% Thr:
0
0
0
0
73
0
0
55
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
10
0
0
73
10
10
0
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _