Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PURA All Species: 22.42
Human Site: Y155 Identified Species: 49.33
UniProt: Q00577 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q00577 NP_005850.1 322 34911 Y155 L V R E N R K Y Y M D L K E N
Chimpanzee Pan troglodytes XP_001136727 295 32969 P151 R Q T V N R G P G L G S T Q G
Rhesus Macaque Macaca mulatta XP_001085737 322 34991 Y155 L V R E N R K Y Y M D L K E N
Dog Lupus familis XP_544287 404 42773 Y237 L V R E N R K Y Y M D L K E N
Cat Felis silvestris
Mouse Mus musculus P42669 321 34865 Y154 L V R E N R K Y Y M D L K E N
Rat Rattus norvegicus Q68A21 315 33399 R143 L D L K E N Q R G R F L R I R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426295 336 38538 Y172 I E R D N R K Y Y L D L K E N
Frog Xenopus laevis Q8AVS4 328 34968 R144 L D L K E N Q R G R F L R I R
Zebra Danio Brachydanio rerio Q6PHK6 297 32588 F152 T V N R G P G F G V G G G G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_726579 274 30978 L137 Y R R Y Y L D L K E N A R G R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784262 259 29404 Y121 I V K E N R R Y Y L D L K E N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.3 99.6 79.6 N.A. 99.3 69.5 N.A. N.A. 50.5 67.3 67.6 N.A. 41.2 N.A. N.A. 46.5
Protein Similarity: 100 91.3 99.6 79.6 N.A. 99.3 77.9 N.A. N.A. 64.2 75.3 76.7 N.A. 58.7 N.A. N.A. 59.9
P-Site Identity: 100 13.3 100 100 N.A. 100 13.3 N.A. N.A. 73.3 13.3 6.6 N.A. 6.6 N.A. N.A. 73.3
P-Site Similarity: 100 26.6 100 100 N.A. 100 33.3 N.A. N.A. 93.3 33.3 20 N.A. 20 N.A. N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 19 0 10 0 0 10 0 0 0 55 0 0 0 0 % D
% Glu: 0 10 0 46 19 0 0 0 0 10 0 0 0 55 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 19 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 19 0 37 0 19 10 10 19 19 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 19 0 0 0 0 0 0 0 0 0 0 0 0 19 0 % I
% Lys: 0 0 10 19 0 0 46 0 10 0 0 0 55 0 0 % K
% Leu: 55 0 19 0 0 10 0 10 0 28 0 73 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 37 0 0 0 0 0 % M
% Asn: 0 0 10 0 64 19 0 0 0 0 10 0 0 0 55 % N
% Pro: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 0 19 0 0 0 0 0 0 10 0 % Q
% Arg: 10 10 55 10 0 64 10 19 0 19 0 0 28 0 28 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % S
% Thr: 10 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % T
% Val: 0 55 0 10 0 0 0 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 10 10 0 0 55 55 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _