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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC42EP1
All Species:
12.73
Human Site:
S152
Identified Species:
31.11
UniProt:
Q00587
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00587
NP_689449.1
391
40295
S152
T
S
S
T
D
G
H
S
S
Y
G
L
D
S
G
Chimpanzee
Pan troglodytes
XP_511657
356
37938
L139
T
S
K
L
P
K
S
L
S
S
S
P
V
K
K
Rhesus Macaque
Macaca mulatta
XP_001086940
398
41013
S152
S
S
S
M
D
G
H
S
S
Y
G
L
D
S
G
Dog
Lupus familis
XP_538388
164
17152
Cat
Felis silvestris
Mouse
Mus musculus
Q91W92
409
43077
S152
A
S
S
T
D
G
H
S
G
Y
G
L
E
S
G
Rat
Rattus norvegicus
A1A5P0
388
41010
S152
A
S
S
T
D
G
R
S
G
Y
G
L
E
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510409
264
27904
S49
F
G
S
P
H
R
G
S
P
L
Q
E
H
L
G
Chicken
Gallus gallus
XP_429544
318
34612
P103
P
E
P
P
A
I
S
P
I
I
K
N
A
V
S
Frog
Xenopus laevis
NP_001108249
324
36267
V108
S
P
I
I
K
N
A
V
S
L
P
Q
L
T
K
Zebra Danio
Brachydanio rerio
XP_001345383
351
38046
F136
G
C
P
V
K
V
L
F
P
S
S
P
K
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.7
90.6
37
N.A.
72.1
65.7
N.A.
39.6
36.5
23.5
30.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
36.5
91.4
39.1
N.A.
75.5
70.8
N.A.
45
45
39.1
43.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
86.6
0
N.A.
80
73.3
N.A.
20
0
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
93.3
0
N.A.
86.6
80
N.A.
20
0
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
0
10
0
10
0
0
0
0
0
10
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
40
0
0
0
0
0
0
0
20
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
10
20
0
0
% E
% Phe:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
0
40
10
0
20
0
40
0
0
0
50
% G
% His:
0
0
0
0
10
0
30
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
10
10
0
10
0
0
10
10
0
0
0
0
0
% I
% Lys:
0
0
10
0
20
10
0
0
0
0
10
0
10
10
20
% K
% Leu:
0
0
0
10
0
0
10
10
0
20
0
40
10
10
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% N
% Pro:
10
10
20
20
10
0
0
10
20
0
10
20
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% Q
% Arg:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% R
% Ser:
20
50
50
0
0
0
20
50
40
20
20
0
0
40
10
% S
% Thr:
20
0
0
30
0
0
0
0
0
0
0
0
0
20
0
% T
% Val:
0
0
0
10
0
10
0
10
0
0
0
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
40
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _