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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC42EP1 All Species: 9.39
Human Site: S365 Identified Species: 22.96
UniProt: Q00587 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q00587 NP_689449.1 391 40295 S365 W R A P Q A G S R T P V P S T
Chimpanzee Pan troglodytes XP_511657 356 37938 S336 D R A Q A A V S R Q P D K E F
Rhesus Macaque Macaca mulatta XP_001086940 398 41013 S372 W R A P Q A H S R T P V P S T
Dog Lupus familis XP_538388 164 17152 A145 F T F D R S P A T S T D G R S
Cat Felis silvestris
Mouse Mus musculus Q91W92 409 43077 V383 W S T P P A S V R A P V P T S
Rat Rattus norvegicus A1A5P0 388 41010 S362 W S A P P A S S R A P V P S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510409 264 27904 V245 E F S V P A T V Q A D S F E F
Chicken Gallus gallus XP_429544 318 34612 G299 G Y T G T R G G R S N S F E Y
Frog Xenopus laevis NP_001108249 324 36267 Q304 S G I T E S E Q S S R C L T T
Zebra Danio Brachydanio rerio XP_001345383 351 38046 N332 G L R N T N T N N S H R R A P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 20.7 90.6 37 N.A. 72.1 65.7 N.A. 39.6 36.5 23.5 30.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 36.5 91.4 39.1 N.A. 75.5 70.8 N.A. 45 45 39.1 43.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 40 93.3 0 N.A. 46.6 73.3 N.A. 6.6 13.3 6.6 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 40 93.3 40 N.A. 60 73.3 N.A. 20 20 33.3 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 40 0 10 60 0 10 0 30 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 10 0 0 10 0 0 0 0 0 0 10 20 0 0 0 % D
% Glu: 10 0 0 0 10 0 10 0 0 0 0 0 0 30 0 % E
% Phe: 10 10 10 0 0 0 0 0 0 0 0 0 20 0 20 % F
% Gly: 20 10 0 10 0 0 20 10 0 0 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % K
% Leu: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 10 0 10 10 0 10 0 0 0 0 % N
% Pro: 0 0 0 40 30 0 10 0 0 0 50 0 40 0 10 % P
% Gln: 0 0 0 10 20 0 0 10 10 10 0 0 0 0 0 % Q
% Arg: 0 30 10 0 10 10 0 0 60 0 10 10 10 10 0 % R
% Ser: 10 20 10 0 0 20 20 40 10 40 0 20 0 30 20 % S
% Thr: 0 10 20 10 20 0 20 0 10 20 10 0 0 20 40 % T
% Val: 0 0 0 10 0 0 10 20 0 0 0 40 0 0 0 % V
% Trp: 40 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _