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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NFKB2 All Species: 22.12
Human Site: Y821 Identified Species: 54.07
UniProt: Q00653 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q00653 NP_001070961.1 900 96749 Y821 S G S L L R S Y E L A G G D L
Chimpanzee Pan troglodytes XP_001168576 837 90846 S779 S L P L S P A S T R Q Q I D E
Rhesus Macaque Macaca mulatta XP_001104566 876 94023 R819 S P S G S L L R S Y E L A G G
Dog Lupus familis XP_850995 899 96492 Y821 S G S L L R S Y K L A G G D L
Cat Felis silvestris
Mouse Mus musculus Q9WTK5 899 96814 Y821 S G S L L R S Y K L A G G D L
Rat Rattus norvegicus NP_001008350 898 96721 Y820 S G S L L R S Y K L A G G D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P98150 906 99648 E828 A S A L R S Y E L P G G S L G
Frog Xenopus laevis O73630 958 105836 Y871 T E S L L R N Y E L A G G N L
Zebra Danio Brachydanio rerio NP_001001840 902 98760 Y839 C Q K L L E S Y Q L S G G P V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999819 1125 124026 F1058 T A V I L K Q F E A M D G T I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 40.1 95.1 92.5 N.A. 91.7 90.8 N.A. N.A. 66.8 50.9 49.6 N.A. N.A. N.A. N.A. 33.4
Protein Similarity: 100 55 96 95.1 N.A. 94.8 94.1 N.A. N.A. 76.7 65.9 65.1 N.A. N.A. N.A. N.A. 50.4
P-Site Identity: 100 20 13.3 93.3 N.A. 93.3 93.3 N.A. N.A. 13.3 73.3 46.6 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 26.6 13.3 100 N.A. 100 100 N.A. N.A. 26.6 93.3 66.6 N.A. N.A. N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 10 0 0 0 10 0 0 10 50 0 10 0 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 10 0 50 0 % D
% Glu: 0 10 0 0 0 10 0 10 30 0 10 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 40 0 10 0 0 0 0 0 0 10 70 70 10 20 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 10 0 10 % I
% Lys: 0 0 10 0 0 10 0 0 30 0 0 0 0 0 0 % K
% Leu: 0 10 0 80 70 10 10 0 10 60 0 10 0 10 50 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 0 % N
% Pro: 0 10 10 0 0 10 0 0 0 10 0 0 0 10 0 % P
% Gln: 0 10 0 0 0 0 10 0 10 0 10 10 0 0 0 % Q
% Arg: 0 0 0 0 10 50 0 10 0 10 0 0 0 0 0 % R
% Ser: 60 10 60 0 20 10 50 10 10 0 10 0 10 0 0 % S
% Thr: 20 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % T
% Val: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 60 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _