KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCB2
All Species:
16.06
Human Site:
S863
Identified Species:
32.12
UniProt:
Q00722
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00722
NP_004564.2
1185
134024
S863
N
G
A
L
A
P
T
S
N
G
S
P
A
A
R
Chimpanzee
Pan troglodytes
XP_001141721
1185
134063
S863
N
G
A
L
A
P
T
S
N
G
S
P
A
A
R
Rhesus Macaque
Macaca mulatta
XP_001095135
1181
134067
S859
N
G
A
L
A
P
R
S
N
G
S
P
A
A
R
Dog
Lupus familis
XP_544615
1188
134303
S863
N
G
P
L
A
P
V
S
N
G
S
A
A
A
R
Cat
Felis silvestris
Mouse
Mus musculus
A3KGF7
1181
134528
G863
N
G
A
P
V
S
A
G
N
G
S
T
A
P
G
Rat
Rattus norvegicus
O89040
1183
134864
G866
N
G
A
P
V
S
A
G
N
G
S
T
A
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513474
1217
138978
Q882
P
S
Q
V
V
H
S
Q
P
T
P
G
S
V
K
Chicken
Gallus gallus
Q2VRL0
637
72514
I434
T
S
R
F
I
T
R
I
Y
P
K
G
T
R
A
Frog
Xenopus laevis
Q32NH8
758
87399
Y555
L
R
T
D
S
S
N
Y
N
P
Q
D
M
W
N
Zebra Danio
Brachydanio rerio
NP_001116245
1244
141781
S894
P
I
F
P
L
P
S
S
P
T
L
P
S
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
T978
S
L
D
Q
S
V
S
T
S
I
R
Q
V
E
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q944C2
578
66234
A375
L
L
R
I
Y
P
K
A
T
R
V
N
S
S
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.1
91.5
N.A.
85.9
85.9
N.A.
44.7
21.5
23.9
42.5
N.A.
35.8
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
97.5
94.9
N.A.
90.7
90.8
N.A.
65.3
33.9
35.4
61.1
N.A.
54
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
46.6
46.6
N.A.
0
0
6.6
20
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
80
N.A.
46.6
46.6
N.A.
26.6
0
13.3
33.3
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
31.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
42
0
34
0
17
9
0
0
0
9
50
34
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
9
0
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% E
% Phe:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
50
0
0
0
0
0
17
0
50
0
17
0
0
17
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
9
9
0
0
9
0
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
9
% K
% Leu:
17
17
0
34
9
0
0
0
0
0
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
50
0
0
0
0
0
9
0
59
0
0
9
0
0
17
% N
% Pro:
17
0
9
25
0
50
0
0
17
17
9
34
0
17
9
% P
% Gln:
0
0
9
9
0
0
0
9
0
0
9
9
0
0
0
% Q
% Arg:
0
9
17
0
0
0
17
0
0
9
9
0
0
9
34
% R
% Ser:
9
17
0
0
17
25
25
42
9
0
50
0
25
9
9
% S
% Thr:
9
0
9
0
0
9
17
9
9
17
0
17
9
0
0
% T
% Val:
0
0
0
9
25
9
9
0
0
0
9
0
9
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
0
9
0
0
9
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _