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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REEP5
All Species:
17.27
Human Site:
S150
Identified Species:
31.67
UniProt:
Q00765
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00765
NP_005660.4
189
21493
S150
P
F
F
L
K
H
E
S
Q
M
D
S
V
V
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082843
322
35914
S283
P
F
F
L
K
H
E
S
Q
M
D
S
V
V
K
Dog
Lupus familis
XP_536283
514
54312
S475
P
V
F
L
K
H
E
S
Q
V
D
T
M
V
N
Cat
Felis silvestris
Mouse
Mus musculus
Q60870
185
21032
Q147
I
F
L
R
H
E
S
Q
V
D
S
V
V
K
D
Rat
Rattus norvegicus
B2RZ37
189
21412
S150
P
I
F
L
K
H
E
S
Q
V
D
S
V
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507345
189
21424
S150
P
F
F
L
K
H
E
S
Q
M
D
S
V
V
K
Chicken
Gallus gallus
XP_001233336
302
33303
A263
P
F
F
L
K
H
E
A
Q
L
D
N
V
V
K
Frog
Xenopus laevis
NP_001089690
189
21407
G150
P
F
F
L
K
H
E
G
E
M
D
R
L
V
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624070
178
20762
Y140
R
N
G
S
L
I
L
Y
H
C
I
I
R
P
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780122
198
22388
A149
P
F
I
L
K
H
Q
A
E
I
E
D
S
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q6NLY8
200
22135
R156
R
S
H
Q
G
E
I
R
F
V
R
A
M
I
A
Baker's Yeast
Sacchar. cerevisiae
Q12402
180
20251
K142
G
A
R
M
I
Y
Q
K
I
V
A
P
L
T
D
Red Bread Mold
Neurospora crassa
Q871R7
168
19003
F130
L
W
L
S
L
P
T
F
K
G
A
E
T
I
F
Conservation
Percent
Protein Identity:
100
N.A.
58.7
31.5
N.A.
89.9
94.1
N.A.
91.5
53.9
78.3
N.A.
N.A.
N.A.
50.2
N.A.
48.9
Protein Similarity:
100
N.A.
58.7
34.4
N.A.
95.7
98.9
N.A.
97.8
59.5
93.1
N.A.
N.A.
N.A.
67.7
N.A.
68.1
P-Site Identity:
100
N.A.
100
66.6
N.A.
13.3
86.6
N.A.
100
80
73.3
N.A.
N.A.
N.A.
0
N.A.
33.3
P-Site Similarity:
100
N.A.
100
86.6
N.A.
13.3
93.3
N.A.
100
100
86.6
N.A.
N.A.
N.A.
0
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.5
33.3
31.2
Protein Similarity:
N.A.
N.A.
N.A.
50
54.5
50.7
P-Site Identity:
N.A.
N.A.
N.A.
0
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
16
0
0
16
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
54
8
0
0
24
% D
% Glu:
0
0
0
0
0
16
54
0
16
0
8
8
0
0
0
% E
% Phe:
0
54
54
0
0
0
0
8
8
0
0
0
0
0
8
% F
% Gly:
8
0
8
0
8
0
0
8
0
8
0
0
0
0
0
% G
% His:
0
0
8
0
8
62
0
0
8
0
0
0
0
0
0
% H
% Ile:
8
8
8
0
8
8
8
0
8
8
8
8
0
16
0
% I
% Lys:
0
0
0
0
62
0
0
8
8
0
0
0
0
8
47
% K
% Leu:
8
0
16
62
16
0
8
0
0
8
0
0
16
8
0
% L
% Met:
0
0
0
8
0
0
0
0
0
31
0
0
16
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
16
% N
% Pro:
62
0
0
0
0
8
0
0
0
0
0
8
0
8
0
% P
% Gln:
0
0
0
8
0
0
16
8
47
0
0
0
0
0
0
% Q
% Arg:
16
0
8
8
0
0
0
8
0
0
8
8
8
0
0
% R
% Ser:
0
8
0
16
0
0
8
39
0
0
8
31
8
0
0
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
0
8
8
8
0
% T
% Val:
0
8
0
0
0
0
0
0
8
31
0
8
47
54
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _