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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HNRNPU All Species: 21.21
Human Site: Y753 Identified Species: 51.85
UniProt: Q00839 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q00839 NP_004492.2 825 90584 Y753 S G G I G Y P Y P R A P V F P
Chimpanzee Pan troglodytes XP_514313 602 67780 P531 G G I G Y P Y P R A P V F P G
Rhesus Macaque Macaca mulatta XP_001102264 804 88139 G733 G G A P G N R G G Y N R R G N
Dog Lupus familis XP_537222 722 79592 Y650 S G G I G Y P Y P R G P V F P
Cat Felis silvestris
Mouse Mus musculus Q8VEK3 800 87899 Y728 S G G I G Y P Y P R G P V F P
Rat Rattus norvegicus NP_476480 798 87714 Y726 S G G I G Y P Y P R G P V F P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513552 687 76851 Y615 S G G V G Y P Y P R A P V Y P
Chicken Gallus gallus XP_419539 694 77513 Y622 S G A I G Y P Y P R G P V F P
Frog Xenopus laevis NP_001084218 774 85852 A701 V G Y P Y P R A P V Y P N R G
Zebra Danio Brachydanio rerio NP_001028767 788 87732 Q698 G M S P R G G Q M R G N M A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 72.6 89.6 86.4 N.A. 94.3 93.8 N.A. 71.1 72.2 69.8 59.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 72.8 90.7 86.7 N.A. 95.5 95 N.A. 75.2 76 78.9 70.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 13.3 93.3 N.A. 93.3 93.3 N.A. 86.6 86.6 20 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 13.3 93.3 N.A. 93.3 93.3 N.A. 100 86.6 20 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 0 0 0 0 10 0 10 20 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 50 0 % F
% Gly: 30 90 50 10 70 10 10 10 10 0 50 0 0 10 20 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 50 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 10 0 0 0 0 0 0 10 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 10 10 10 0 10 % N
% Pro: 0 0 0 30 0 20 60 10 70 0 10 70 0 10 60 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 10 0 20 0 10 70 0 10 10 10 0 % R
% Ser: 60 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 10 0 0 10 0 0 0 0 0 10 0 10 60 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 20 60 10 60 0 10 10 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _