KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1B
All Species:
16.97
Human Site:
S2144
Identified Species:
37.33
UniProt:
Q00975
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00975
NP_000709.1
2339
262496
S2144
E
P
P
K
P
K
P
S
L
S
S
H
P
T
S
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
S2589
E
P
P
K
P
K
P
S
L
S
S
H
P
T
S
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
S2168
P
K
P
R
P
L
L
S
Y
S
S
L
I
R
H
Dog
Lupus familis
XP_537779
2046
229120
S1853
S
Q
P
K
P
S
L
S
S
H
P
T
S
P
T
Cat
Felis silvestris
Mouse
Mus musculus
O55017
2327
261463
S2132
E
P
P
Q
L
M
P
S
L
S
S
H
P
T
S
Rat
Rattus norvegicus
Q02294
2336
262238
S2141
E
P
P
Q
P
K
P
S
L
S
S
H
P
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
S1996
A
V
A
G
L
D
S
S
K
A
H
K
H
S
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q2XVR3
1829
207718
N1636
S
M
D
I
P
I
V
N
G
D
K
I
H
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
R1658
P
A
R
L
Q
E
M
R
E
R
D
R
L
G
Y
Honey Bee
Apis mellifera
NP_001159376
1904
215872
H1711
V
E
I
Q
R
H
T
H
H
P
H
P
S
Q
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
R1773
S
G
G
S
S
H
R
R
P
S
P
G
W
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
54.2
80.1
N.A.
91.9
92.1
N.A.
N.A.
38.3
N.A.
20.7
N.A.
44.7
47.6
N.A.
39.5
Protein Similarity:
100
82.3
65.5
82.2
N.A.
94.4
94.5
N.A.
N.A.
53.3
N.A.
36
N.A.
56
58.7
N.A.
52.4
P-Site Identity:
100
100
33.3
26.6
N.A.
80
86.6
N.A.
N.A.
6.6
N.A.
6.6
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
100
40
33.3
N.A.
86.6
93.3
N.A.
N.A.
20
N.A.
20
N.A.
6.6
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
0
0
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
10
0
0
0
10
10
0
0
0
0
% D
% Glu:
37
10
0
0
0
10
0
0
10
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
10
0
0
0
0
10
0
0
10
0
10
0
% G
% His:
0
0
0
0
0
19
0
10
10
10
19
37
19
0
10
% H
% Ile:
0
0
10
10
0
10
0
0
0
0
0
10
10
10
0
% I
% Lys:
0
10
0
28
0
28
0
0
10
0
10
10
0
0
0
% K
% Leu:
0
0
0
10
19
10
19
0
37
0
0
10
10
0
0
% L
% Met:
0
10
0
0
0
10
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
19
37
55
0
55
0
37
0
10
10
19
10
37
10
10
% P
% Gln:
0
10
0
28
10
0
0
0
0
0
0
0
0
10
10
% Q
% Arg:
0
0
10
10
10
0
10
19
0
10
0
10
0
19
0
% R
% Ser:
28
0
0
10
10
10
10
64
10
55
46
0
19
19
37
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
10
0
28
10
% T
% Val:
10
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _