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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CACNA1B All Species: 9.09
Human Site: S944 Identified Species: 20
UniProt: Q00975 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q00975 NP_000709.1 2339 262496 S944 A H R H Q D P S K E C A G A K
Chimpanzee Pan troglodytes XP_520396 2784 310342 S1393 A H R H Q D P S K E C A G A K
Rhesus Macaque Macaca mulatta XP_001110352 2383 269535 S940 A S R S R S A S Q E R S L D E
Dog Lupus familis XP_537779 2046 229120 V723 L G R D G P R V P A G G K A R
Cat Felis silvestris
Mouse Mus musculus O55017 2327 261463 S936 A H R H A Q D S S K E G T A P
Rat Rattus norvegicus Q02294 2336 262238 G958 A P V L V P K G E R R A R H R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus O73700 2190 249326 A779 A V D N L A D A E S L N T A Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q2XVR3 1829 207718 Q506 E L S A E E D Q K S L S S K H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91645 1851 212452 G527 V I W S E V K G G S F G L S V
Honey Bee Apis mellifera NP_001159376 1904 215872 N581 V I V L V F F N T V C V A V E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001186699 1966 222605 E643 K L D Q E E D E E N R Q A A A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.1 54.2 80.1 N.A. 91.9 92.1 N.A. N.A. 38.3 N.A. 20.7 N.A. 44.7 47.6 N.A. 39.5
Protein Similarity: 100 82.3 65.5 82.2 N.A. 94.4 94.5 N.A. N.A. 53.3 N.A. 36 N.A. 56 58.7 N.A. 52.4
P-Site Identity: 100 100 26.6 13.3 N.A. 40 13.3 N.A. N.A. 13.3 N.A. 6.6 N.A. 0 6.6 N.A. 6.6
P-Site Similarity: 100 100 53.3 20 N.A. 46.6 26.6 N.A. N.A. 40 N.A. 26.6 N.A. 13.3 20 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 55 0 0 10 10 10 10 10 0 10 0 28 19 55 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 28 0 0 0 0 % C
% Asp: 0 0 19 10 0 19 37 0 0 0 0 0 0 10 0 % D
% Glu: 10 0 0 0 28 19 0 10 28 28 10 0 0 0 19 % E
% Phe: 0 0 0 0 0 10 10 0 0 0 10 0 0 0 0 % F
% Gly: 0 10 0 0 10 0 0 19 10 0 10 28 19 0 0 % G
% His: 0 28 0 28 0 0 0 0 0 0 0 0 0 10 10 % H
% Ile: 0 19 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 0 19 0 28 10 0 0 10 10 19 % K
% Leu: 10 19 0 19 10 0 0 0 0 0 19 0 19 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 10 0 10 0 10 0 0 0 % N
% Pro: 0 10 0 0 0 19 19 0 10 0 0 0 0 0 10 % P
% Gln: 0 0 0 10 19 10 0 10 10 0 0 10 0 0 10 % Q
% Arg: 0 0 46 0 10 0 10 0 0 10 28 0 10 0 19 % R
% Ser: 0 10 10 19 0 10 0 37 10 28 0 19 10 10 0 % S
% Thr: 0 0 0 0 0 0 0 0 10 0 0 0 19 0 0 % T
% Val: 19 10 19 0 19 10 0 10 0 10 0 10 0 10 10 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _