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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRF9
All Species:
9.39
Human Site:
S140
Identified Species:
22.96
UniProt:
Q00978
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00978
NP_006075.3
393
43696
S140
R
Q
H
S
S
V
S
S
E
R
K
E
E
E
D
Chimpanzee
Pan troglodytes
XP_001167223
392
43518
S139
K
R
H
H
S
S
V
S
S
E
R
E
E
E
E
Rhesus Macaque
Macaca mulatta
XP_001084409
426
48303
C138
N
E
V
T
E
M
E
C
G
R
S
E
I
D
E
Dog
Lupus familis
XP_860263
410
45101
S139
K
R
H
H
S
S
V
S
S
E
R
E
E
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61179
399
44592
S134
Q
K
S
P
C
K
R
S
I
S
C
V
S
P
E
Rat
Rattus norvegicus
P23570
328
37046
A79
P
D
P
K
T
W
K
A
N
F
R
C
A
M
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507292
427
49638
R140
V
T
E
M
D
C
N
R
S
E
I
D
D
L
M
Chicken
Gallus gallus
Q90871
425
49152
S141
G
D
M
D
C
S
P
S
A
I
D
D
L
M
K
Frog
Xenopus laevis
NP_001084846
397
44347
G140
K
S
N
T
V
I
A
G
S
S
S
D
D
E
I
Zebra Danio
Brachydanio rerio
NP_998044
392
44392
S130
S
A
V
N
P
V
I
S
Q
D
S
D
C
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
27.2
77
N.A.
69.6
22.8
N.A.
29
30.5
38
35.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.4
45.5
84.3
N.A.
79.4
40.7
N.A.
47
47
56.4
51.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
40
13.3
33.3
N.A.
6.6
0
N.A.
0
6.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
66.6
46.6
66.6
N.A.
26.6
26.6
N.A.
20
13.3
53.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
10
10
10
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
20
10
0
10
0
0
10
10
10
0
0
% C
% Asp:
0
20
0
10
10
0
0
0
0
10
10
40
20
20
10
% D
% Glu:
0
10
10
0
10
0
10
0
10
30
0
40
30
30
40
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% G
% His:
0
0
30
20
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
10
0
10
10
10
0
10
0
10
% I
% Lys:
30
10
0
10
0
10
10
0
0
0
10
0
0
0
20
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% L
% Met:
0
0
10
10
0
10
0
0
0
0
0
0
0
20
10
% M
% Asn:
10
0
10
10
0
0
10
0
10
0
0
0
0
0
10
% N
% Pro:
10
0
10
10
10
0
10
0
0
0
0
0
0
10
0
% P
% Gln:
10
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
10
20
0
0
0
0
10
10
0
20
30
0
0
0
0
% R
% Ser:
10
10
10
10
30
30
10
60
40
20
30
0
10
10
0
% S
% Thr:
0
10
0
20
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
20
0
10
20
20
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _