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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
U2AF1
All Species:
27.27
Human Site:
S195
Identified Species:
60
UniProt:
Q01081
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01081
NP_006749.1
240
27872
S195
R
R
R
K
K
H
R
S
R
S
R
S
R
E
R
Chimpanzee
Pan troglodytes
XP_001137466
677
72801
S632
R
R
R
K
K
H
R
S
R
S
R
S
R
E
R
Rhesus Macaque
Macaca mulatta
XP_001118538
450
49657
S405
R
R
R
K
K
H
R
S
R
S
R
S
R
E
R
Dog
Lupus familis
XP_535599
301
34429
S256
R
R
R
K
K
H
R
S
R
S
R
S
R
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D883
239
27796
S195
R
R
R
K
K
H
R
S
R
S
R
S
R
E
R
Rat
Rattus norvegicus
Q7TP17
220
25817
L181
L
R
P
I
S
R
N
L
R
R
Q
L
Y
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511817
308
34702
S255
R
R
R
K
K
H
R
S
R
S
R
S
R
E
R
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089860
245
28258
S195
R
R
R
K
K
H
R
S
R
S
R
S
R
E
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94535
264
29858
R197
R
R
R
R
A
R
S
R
S
R
S
P
G
R
R
Honey Bee
Apis mellifera
XP_397281
242
28274
R197
R
K
K
G
G
K
G
R
S
R
S
R
S
R
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FMY5
283
33213
R194
R
Y
R
R
S
Y
R
R
G
S
R
S
R
S
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.4
53.3
78.4
N.A.
99.5
76.6
N.A.
74
N.A.
96.7
N.A.
N.A.
71.9
73.5
N.A.
N.A.
Protein Similarity:
100
35.4
53.3
79
N.A.
99.5
83.7
N.A.
75.9
N.A.
97.5
N.A.
N.A.
78.4
80.5
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
20
N.A.
100
N.A.
100
N.A.
N.A.
26.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
100
N.A.
100
N.A.
N.A.
33.3
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
50.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
64
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
10
0
10
0
10
0
0
0
10
10
0
% G
% His:
0
0
0
0
0
64
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
10
64
64
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
91
82
82
19
0
19
73
28
73
28
73
10
73
19
91
% R
% Ser:
0
0
0
0
19
0
10
64
19
73
19
73
10
10
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
10
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _