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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TIAL1 All Species: 18.79
Human Site: S46 Identified Species: 34.44
UniProt: Q01085 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q01085 NP_001029097.1 375 41591 S46 K M I T E H T S N D P Y C F V
Chimpanzee Pan troglodytes XP_001154825 563 61985 G72 L L F T S Q R G R A P A A P L
Rhesus Macaque Macaca mulatta XP_001098686 375 41755 G44 K M I M D T A G N D P Y C F V
Dog Lupus familis XP_865325 381 42336 S46 K M I T E H T S N D P Y C F V
Cat Felis silvestris
Mouse Mus musculus P70318 392 43370 D46 K M I T E Q P D S R R V N S S
Rat Rattus norvegicus Q9EPH8 636 70682 T48 R V C R D M I T R R S L G Y A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514793 386 43037 S60 F S V L Q H T S N D P Y C F V
Chicken Gallus gallus NP_989687 388 42938 D45 K M I T E Q P D S S R R V N S
Frog Xenopus laevis P20965 633 70449 T48 R V C R D M I T R R S L G Y A
Zebra Danio Brachydanio rerio NP_957426 370 41210 S45 K M I T E H T S N D P Y C F V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09442 388 40990 T50 N M P K D R V T A N H Q G F G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42731 629 68654 T73 R V C R D L V T R R S L G Y G
Baker's Yeast Sacchar. cerevisiae P32588 453 50771 N112 K I M I D K N N K N V N Y A F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.3 80 98.4 N.A. 94.9 22 N.A. 85.2 94 20.7 85.8 N.A. N.A. N.A. 22.1 N.A.
Protein Similarity: 100 62.1 87.4 98.4 N.A. 95.1 32.3 N.A. 89.6 94.3 32.2 92.2 N.A. N.A. N.A. 37.3 N.A.
P-Site Identity: 100 13.3 66.6 100 N.A. 33.3 0 N.A. 66.6 33.3 0 100 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 100 26.6 73.3 100 N.A. 40 33.3 N.A. 80 40 33.3 100 N.A. N.A. N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.3 24 N.A.
Protein Similarity: N.A. N.A. N.A. 34.5 39.9 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 0 8 8 0 8 8 8 16 % A
% Cys: 0 0 24 0 0 0 0 0 0 0 0 0 39 0 0 % C
% Asp: 0 0 0 0 47 0 0 16 0 39 0 0 0 0 0 % D
% Glu: 0 0 0 0 39 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 8 0 8 0 0 0 0 0 0 0 0 0 0 47 8 % F
% Gly: 0 0 0 0 0 0 0 16 0 0 0 0 31 0 16 % G
% His: 0 0 0 0 0 31 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 8 47 8 0 0 16 0 0 0 0 0 0 0 0 % I
% Lys: 54 0 0 8 0 8 0 0 8 0 0 0 0 0 0 % K
% Leu: 8 8 0 8 0 8 0 0 0 0 0 24 0 0 8 % L
% Met: 0 54 8 8 0 16 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 8 8 39 16 0 8 8 8 0 % N
% Pro: 0 0 8 0 0 0 16 0 0 0 47 0 0 8 0 % P
% Gln: 0 0 0 0 8 24 0 0 0 0 0 8 0 0 0 % Q
% Arg: 24 0 0 24 0 8 8 0 31 31 16 8 0 0 0 % R
% Ser: 0 8 0 0 8 0 0 31 16 8 24 0 0 8 16 % S
% Thr: 0 0 0 47 0 8 31 31 0 0 0 0 0 0 0 % T
% Val: 0 24 8 0 0 0 16 0 0 0 8 8 8 0 39 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 39 8 24 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _