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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INSM1 All Species: 8.79
Human Site: S347 Identified Species: 21.48
UniProt: Q01101 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q01101 NP_002187.1 510 52923 S347 R E A P G G G S D R D T P S P
Chimpanzee Pan troglodytes XP_001144246 510 52987 S347 R E A P G G G S D R D T P S P
Rhesus Macaque Macaca mulatta XP_001088093 568 59794 V408 Q G P Y T E G V F G R R V P V
Dog Lupus familis XP_849395 356 38694 K230 R R Q A Y L R K H L L A H H Q
Cat Felis silvestris
Mouse Mus musculus Q63ZV0 521 54031 S353 E A A G G G S S D R D T P S P
Rat Rattus norvegicus Q99PJ7 500 57264 R325 P C P D C E R R F S S S S R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505849 397 42525 G249 A P D P A R P G V D R D T P S
Chicken Gallus gallus
Frog Xenopus laevis NP_001104189 433 47563 E286 V P A V Q P K E E A L S D R D
Zebra Danio Brachydanio rerio NP_955952 453 49550 P301 E E L R A E F P S D R D T P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001198951 484 53797 S329 P R S T P S P S S T Y N N N N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 39.7 58.2 N.A. 90.7 22.5 N.A. 57 N.A. 57.2 56.4 N.A. N.A. N.A. N.A. 20.3
Protein Similarity: 100 99.4 48.2 62.5 N.A. 91.9 32.1 N.A. 60.2 N.A. 63.9 65.8 N.A. N.A. N.A. N.A. 31.5
P-Site Identity: 100 100 6.6 6.6 N.A. 73.3 0 N.A. 6.6 N.A. 6.6 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 13.3 6.6 N.A. 73.3 6.6 N.A. 6.6 N.A. 20 6.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 40 10 20 0 0 0 0 10 0 10 0 0 0 % A
% Cys: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 10 0 0 0 0 30 20 30 20 10 0 10 % D
% Glu: 20 30 0 0 0 30 0 10 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 20 0 0 0 0 0 0 % F
% Gly: 0 10 0 10 30 30 30 10 0 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 10 0 0 0 10 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 0 0 10 0 0 0 10 20 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 10 10 10 % N
% Pro: 20 20 20 30 10 10 20 10 0 0 0 0 30 30 30 % P
% Gln: 10 0 10 0 10 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 30 20 0 10 0 10 20 10 0 30 30 10 0 20 0 % R
% Ser: 0 0 10 0 0 10 10 40 20 10 10 20 10 30 20 % S
% Thr: 0 0 0 10 10 0 0 0 0 10 0 30 20 0 0 % T
% Val: 10 0 0 10 0 0 0 10 10 0 0 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 10 0 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _