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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS2 All Species: 27.58
Human Site: S121 Identified Species: 55.15
UniProt: Q01130 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q01130 NP_003007.2 221 25476 S121 G Y G R R S R S P R R R R R S
Chimpanzee Pan troglodytes Q5R1W5 221 25469 S121 G Y G R R S R S P R R R R R S
Rhesus Macaque Macaca mulatta XP_001106051 201 23176 S101 G Y G R R S R S P R R R R R S
Dog Lupus familis XP_848989 221 25472 S121 G Y G R R T R S P R R R R R S
Cat Felis silvestris
Mouse Mus musculus Q62093 221 25458 S121 G Y G R R S R S P R R R R R S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514814 120 13806 L21 T S L K V D N L T Y R T S P D
Chicken Gallus gallus P30352 221 25506 S121 G Y G R R S R S P R R R R R S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P26686 376 42795 S211 G R G R S R S S S S R S R S R
Honey Bee Apis mellifera XP_393352 176 20938 G77 D A L D A M D G R L L D G R E
Nematode Worm Caenorhab. elegans Q09511 196 22569 Y97 L R V T L A K Y D R P S D E R
Sea Urchin Strong. purpuratus XP_785989 237 27457 A131 G G S R R S S A N C S S Y Y S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22315 303 33711 S203 D S R K D S R S P S R G R S Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 90.5 99.5 N.A. 100 N.A. N.A. 54.2 98.1 N.A. N.A. N.A. 34 61.5 51.5 56.9
Protein Similarity: 100 99.5 90.5 100 N.A. 100 N.A. N.A. 54.2 98.1 N.A. N.A. N.A. 42.2 70.1 65.1 67.5
P-Site Identity: 100 100 100 93.3 N.A. 100 N.A. N.A. 6.6 100 N.A. N.A. N.A. 40 6.6 6.6 33.3
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 13.3 100 N.A. N.A. N.A. 40 6.6 20 40
Percent
Protein Identity: N.A. N.A. N.A. 31.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 40 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 9 9 0 9 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 17 0 0 9 9 9 9 0 9 0 0 9 9 0 9 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 67 9 59 0 0 0 0 9 0 0 0 9 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 17 0 0 9 0 0 0 0 0 0 0 0 % K
% Leu: 9 0 17 0 9 0 0 9 0 9 9 0 0 0 0 % L
% Met: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 9 0 9 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 59 0 9 0 0 9 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 17 9 67 59 9 59 0 9 59 75 50 67 59 17 % R
% Ser: 0 17 9 0 9 59 17 67 9 17 9 25 9 17 59 % S
% Thr: 9 0 0 9 0 9 0 0 9 0 0 9 0 0 0 % T
% Val: 0 0 9 0 9 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 50 0 0 0 0 0 9 0 9 0 0 9 9 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _