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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IL5RA
All Species:
17.58
Human Site:
S380
Identified Species:
42.96
UniProt:
Q01344
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01344
NP_000555.2
420
47685
S380
P
P
I
P
A
P
K
S
N
I
K
D
L
F
V
Chimpanzee
Pan troglodytes
XP_001139026
420
47673
S380
P
P
I
P
A
P
K
S
N
I
K
D
L
F
V
Rhesus Macaque
Macaca mulatta
XP_001100843
420
47694
S380
P
P
I
P
A
P
K
S
N
I
K
D
L
F
V
Dog
Lupus familis
XP_533759
415
46926
S375
P
P
V
P
A
P
K
S
S
I
K
D
F
F
V
Cat
Felis silvestris
Mouse
Mus musculus
P21183
415
46971
S376
P
P
V
P
A
P
K
S
N
I
K
D
L
P
V
Rat
Rattus norvegicus
Q8VHK6
385
44604
F346
F
I
V
P
V
C
L
F
F
I
F
L
L
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521507
333
37890
K294
L
V
I
D
A
T
C
K
Y
S
V
K
I
R
A
Chicken
Gallus gallus
XP_001235031
315
36564
K276
Q
I
R
A
N
H
H
K
C
A
V
N
G
F
W
Frog
Xenopus laevis
NP_001087820
415
47527
I368
K
F
H
L
F
K
K
I
F
P
P
I
P
K
P
Zebra Danio
Brachydanio rerio
NP_001107203
407
46515
C366
T
A
G
V
I
I
F
C
L
S
L
W
I
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
93.5
72.3
N.A.
68.3
23.8
N.A.
47.3
35
30.7
23.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
97.1
80.7
N.A.
80.2
40.2
N.A.
56.6
50.9
53
42.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
86.6
20
N.A.
13.3
6.6
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
33.3
N.A.
20
13.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
60
0
0
0
0
10
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
10
10
10
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
50
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
10
0
0
10
0
10
10
20
0
10
0
10
50
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
10
0
0
10
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
20
40
0
10
10
0
10
0
60
0
10
20
0
0
% I
% Lys:
10
0
0
0
0
10
60
20
0
0
50
10
0
10
0
% K
% Leu:
10
0
0
10
0
0
10
0
10
0
10
10
50
20
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
40
0
0
10
0
0
0
% N
% Pro:
50
50
0
60
0
50
0
0
0
10
10
0
10
10
10
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
0
0
0
0
0
0
50
10
20
0
0
0
0
0
% S
% Thr:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% T
% Val:
0
10
30
10
10
0
0
0
0
0
20
0
0
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _