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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IL5RA All Species: 17.58
Human Site: Y272 Identified Species: 42.96
UniProt: Q01344 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q01344 NP_000555.2 420 47685 Y272 F P I H C F D Y E V K I H N T
Chimpanzee Pan troglodytes XP_001139026 420 47673 Y272 F P I H C F D Y E V K I H N T
Rhesus Macaque Macaca mulatta XP_001100843 420 47694 Y272 F P I H C F D Y E V K I H N A
Dog Lupus familis XP_533759 415 46926 Y267 F P I H C F E Y E V K I Y N T
Cat Felis silvestris
Mouse Mus musculus P21183 415 46971 Y269 F P D H C F N Y E L K I Y N T
Rat Rattus norvegicus Q8VHK6 385 44604 I248 H I S V E N S I D I R M K W S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521507 333 37890 K197 S R T H I Y S K G Q L K L A V
Chicken Gallus gallus XP_001235031 315 36564 G179 L I V I H I N G S S K Y A A I
Frog Xenopus laevis NP_001087820 415 47527 V270 P H Y F V Y E V I I W N L K T
Zebra Danio Brachydanio rerio NP_001107203 407 46515 E269 P P S G Q V P E H C L D Y E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 93.5 72.3 N.A. 68.3 23.8 N.A. 47.3 35 30.7 23.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.2 97.1 80.7 N.A. 80.2 40.2 N.A. 56.6 50.9 53 42.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 86.6 N.A. 73.3 0 N.A. 6.6 6.6 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 100 N.A. 93.3 33.3 N.A. 13.3 20 26.6 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 10 20 10 % A
% Cys: 0 0 0 0 50 0 0 0 0 10 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 30 0 10 0 0 10 0 0 0 % D
% Glu: 0 0 0 0 10 0 20 10 50 0 0 0 0 10 0 % E
% Phe: 50 0 0 10 0 50 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 0 10 10 0 0 0 0 0 0 % G
% His: 10 10 0 60 10 0 0 0 10 0 0 0 30 0 0 % H
% Ile: 0 20 40 10 10 10 0 10 10 20 0 50 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 10 0 0 60 10 10 10 0 % K
% Leu: 10 0 0 0 0 0 0 0 0 10 20 0 20 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 10 20 0 0 0 0 10 0 50 0 % N
% Pro: 20 60 0 0 0 0 10 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % Q
% Arg: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 10 0 20 0 0 0 20 0 10 10 0 0 0 0 10 % S
% Thr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 50 % T
% Val: 0 0 10 10 10 10 0 10 0 40 0 0 0 0 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % W
% Tyr: 0 0 10 0 0 20 0 50 0 0 0 10 30 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _