Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMPD3 All Species: 24.24
Human Site: Y125 Identified Species: 53.33
UniProt: Q01432 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q01432 NP_000471.1 767 88812 Y125 S L P T P A P Y A M P E F Q R
Chimpanzee Pan troglodytes XP_001169861 767 88837 Y125 S L P T P A P Y A M P E F Q R
Rhesus Macaque Macaca mulatta XP_001100194 767 88843 Y125 S Q P T P A P Y A M P E F Q R
Dog Lupus familis XP_534054 777 89815 Y135 S Q P T P A P Y A M P E F Q R
Cat Felis silvestris
Mouse Mus musculus O08739 766 88647 Y125 S K P G P A P Y A M P E Y Q R
Rat Rattus norvegicus O09178 765 88465 Y124 S K P G L A P Y D M P E Y Q R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509865 770 89478 F129 C P V A P V P F A M P E F Q R
Chicken Gallus gallus XP_420973 765 88913 Y122 F L P V Q V P Y D V P E F Q R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_684508 777 89561 P136 S T C S S I S P N F P E Y Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O80452 839 95111 S203 S S M I R S H S V S G D L H G
Baker's Yeast Sacchar. cerevisiae P15274 810 93283 A155 T L K S F A G A P V V N K Q V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.6 95.5 N.A. 94.1 92.9 N.A. 89.7 85.4 N.A. 74 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 99 96.6 N.A. 96.6 96.2 N.A. 93.9 92.1 N.A. 86 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 93.3 N.A. 80 66.6 N.A. 60 60 N.A. 33.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 93.3 N.A. 86.6 73.3 N.A. 66.6 66.6 N.A. 46.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 40.7 40.1 N.A.
Protein Similarity: N.A. N.A. N.A. 56.1 58.6 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 64 0 10 55 0 0 0 0 0 0 % A
% Cys: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 19 0 0 10 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 82 0 0 0 % E
% Phe: 10 0 0 0 10 0 0 10 0 10 0 0 55 0 0 % F
% Gly: 0 0 0 19 0 0 10 0 0 0 10 0 0 0 10 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 19 10 0 0 0 0 0 0 0 0 0 10 0 0 % K
% Leu: 0 37 0 0 10 0 0 0 0 0 0 0 10 0 0 % L
% Met: 0 0 10 0 0 0 0 0 0 64 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 0 0 10 0 0 0 % N
% Pro: 0 10 64 0 55 0 73 10 10 0 82 0 0 0 0 % P
% Gln: 0 19 0 0 10 0 0 0 0 0 0 0 0 91 0 % Q
% Arg: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 82 % R
% Ser: 73 10 0 19 10 10 10 10 0 10 0 0 0 0 0 % S
% Thr: 10 10 0 37 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 10 10 0 19 0 0 10 19 10 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 64 0 0 0 0 28 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _