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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMPD2 All Species: 6.97
Human Site: S292 Identified Species: 13.94
UniProt: Q01433 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q01433 NP_004028.3 879 100688 S292 Q G P D T P V S A D A P V H P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001093312 879 100639 S292 Q G P D T P V S A D A P V H P
Dog Lupus familis XP_852599 799 92011 D271 E V E L P Y P D L Q E F V A D
Cat Felis silvestris
Mouse Mus musculus Q9DBT5 798 92005 D271 E V E L P Y P D L Q E F V A D
Rat Rattus norvegicus Q02356 824 94769 G274 L G L R M V R G V V H V Y T R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_700028 819 94934 V273 M V D G V V H V Y L L K I I D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_727741 774 89333 S247 I Y E N D D E S S E I K Y E Y
Honey Bee Apis mellifera XP_623550 773 88695 F245 V Y A N E E D F T D G K P I L
Nematode Worm Caenorhab. elegans NP_001040752 803 92339 E273 R R N R G V T E I C N D D G S
Sea Urchin Strong. purpuratus XP_792615 845 97202 N274 E I Q Y H P I N A P S K S D P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O80452 839 95111 S276 P W E K E V I S D P S T P K P
Baker's Yeast Sacchar. cerevisiae P15274 810 93283 N273 P D W E F T L N D D D S Y V V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.6 89.5 N.A. 88.6 91.4 N.A. N.A. N.A. N.A. 72.5 N.A. 52.5 54 46.8 48.3
Protein Similarity: 100 N.A. 99.8 90.2 N.A. 89.3 92 N.A. N.A. N.A. N.A. 82 N.A. 67.4 65.9 60.9 63.2
P-Site Identity: 100 N.A. 100 6.6 N.A. 6.6 6.6 N.A. N.A. N.A. N.A. 0 N.A. 6.6 6.6 0 20
P-Site Similarity: 100 N.A. 100 13.3 N.A. 13.3 6.6 N.A. N.A. N.A. N.A. 6.6 N.A. 26.6 13.3 6.6 46.6
Percent
Protein Identity: N.A. N.A. N.A. 42.5 41.7 N.A.
Protein Similarity: N.A. N.A. N.A. 57.4 57.6 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 0 0 0 25 0 17 0 0 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 9 9 17 9 9 9 17 17 34 9 9 9 9 25 % D
% Glu: 25 0 34 9 17 9 9 9 0 9 17 0 0 9 0 % E
% Phe: 0 0 0 0 9 0 0 9 0 0 0 17 0 0 0 % F
% Gly: 0 25 0 9 9 0 0 9 0 0 9 0 0 9 0 % G
% His: 0 0 0 0 9 0 9 0 0 0 9 0 0 17 0 % H
% Ile: 9 9 0 0 0 0 17 0 9 0 9 0 9 17 0 % I
% Lys: 0 0 0 9 0 0 0 0 0 0 0 34 0 9 0 % K
% Leu: 9 0 9 17 0 0 9 0 17 9 9 0 0 0 9 % L
% Met: 9 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 17 0 0 0 17 0 0 9 0 0 0 0 % N
% Pro: 17 0 17 0 17 25 17 0 0 17 0 17 17 0 34 % P
% Gln: 17 0 9 0 0 0 0 0 0 17 0 0 0 0 0 % Q
% Arg: 9 9 0 17 0 0 9 0 0 0 0 0 0 0 9 % R
% Ser: 0 0 0 0 0 0 0 34 9 0 17 9 9 0 9 % S
% Thr: 0 0 0 0 17 9 9 0 9 0 0 9 0 9 0 % T
% Val: 9 25 0 0 9 34 17 9 9 9 0 9 34 9 9 % V
% Trp: 0 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 17 0 9 0 17 0 0 9 0 0 0 25 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _