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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PMP22 All Species: 18.18
Human Site: S64 Identified Species: 44.44
UniProt: Q01453 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q01453 NP_000295.1 160 17891 S64 S P N E W L Q S V Q A T M I L
Chimpanzee Pan troglodytes A5A6N6 167 19216 V64 E Y S T L Q A V Q A T M I L S
Rhesus Macaque Macaca mulatta XP_001082490 160 17829 S64 S P N E W L Q S V Q A T M I L
Dog Lupus familis XP_536648 160 17812 S64 S A N E W L Q S V Q A T M I L
Cat Felis silvestris
Mouse Mus musculus P16646 161 18005 S64 S V S E W L Q S V Q A T M I L
Rat Rattus norvegicus P25094 160 17928 S64 S V S E W L Q S V Q A T M I L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505583 167 19166 S71 V Q A T M I L S T I L C C I A
Chicken Gallus gallus XP_415595 160 17704 V64 T N E W L Q S V Q A M M I L S
Frog Xenopus laevis NP_001087002 159 17507 V64 S N E W L Q S V Q A M M I L S
Zebra Danio Brachydanio rerio NP_958468 157 17605 A62 G D A D W L Q A V Q A L M V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.3 98.7 93.1 N.A. 85.7 86.8 N.A. 46.1 79.3 73.7 51.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 64.6 99.3 96.8 N.A. 93.7 95 N.A. 64 86.8 85.6 71.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 93.3 N.A. 86.6 86.6 N.A. 13.3 0 6.6 53.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 100 93.3 N.A. 93.3 93.3 N.A. 20 20 20 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 20 0 0 0 10 10 0 30 60 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % C
% Asp: 0 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 20 50 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 10 0 0 30 60 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 30 60 10 0 0 0 10 10 0 30 60 % L
% Met: 0 0 0 0 10 0 0 0 0 0 20 30 60 0 0 % M
% Asn: 0 20 30 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 30 60 0 30 60 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 60 0 30 0 0 0 20 60 0 0 0 0 0 0 30 % S
% Thr: 10 0 0 20 0 0 0 0 10 0 10 50 0 0 0 % T
% Val: 10 20 0 0 0 0 0 30 60 0 0 0 0 10 0 % V
% Trp: 0 0 0 20 60 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _