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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PMP22 All Species: 22.42
Human Site: Y130 Identified Species: 54.81
UniProt: Q01453 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q01453 NP_000295.1 160 17891 Y130 E W H L N S D Y S Y G F A Y I
Chimpanzee Pan troglodytes A5A6N6 167 19216 F130 I H H K N A K F Y P V T R E G
Rhesus Macaque Macaca mulatta XP_001082490 160 17829 Y130 E W H L N S D Y S Y G F A Y I
Dog Lupus familis XP_536648 160 17812 Y130 E W H F N S D Y A Y G F T Y I
Cat Felis silvestris
Mouse Mus musculus P16646 161 18005 Y130 E W H V N T D Y S Y G F A Y I
Rat Rattus norvegicus P25094 160 17928 Y130 E W H V N N D Y S Y G F A Y I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505583 167 19166 G137 F Y K E M D G G K Y G Y S F I
Chicken Gallus gallus XP_415595 160 17704 T130 W H E A S E N T S Y G F A Y I
Frog Xenopus laevis NP_001087002 159 17507 S130 W Q T A E V A S Y G F A Y I L
Zebra Danio Brachydanio rerio NP_958468 157 17605 T128 Q W K N D S D T Y G Y A F V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.3 98.7 93.1 N.A. 85.7 86.8 N.A. 46.1 79.3 73.7 51.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 64.6 99.3 96.8 N.A. 93.7 95 N.A. 64 86.8 85.6 71.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 100 80 N.A. 86.6 86.6 N.A. 20 46.6 0 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 86.6 N.A. 100 100 N.A. 46.6 60 6.6 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 20 0 10 10 0 10 0 0 20 50 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 10 60 0 0 0 0 0 0 0 0 % D
% Glu: 50 0 10 10 10 10 0 0 0 0 0 0 0 10 0 % E
% Phe: 10 0 0 10 0 0 0 10 0 0 10 60 10 10 0 % F
% Gly: 0 0 0 0 0 0 10 10 0 20 70 0 0 0 10 % G
% His: 0 20 60 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 70 % I
% Lys: 0 0 20 10 0 0 10 0 10 0 0 0 0 0 0 % K
% Leu: 0 0 0 20 0 0 0 0 0 0 0 0 0 0 20 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 60 10 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % P
% Gln: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % R
% Ser: 0 0 0 0 10 40 0 10 50 0 0 0 10 0 0 % S
% Thr: 0 0 10 0 0 10 0 20 0 0 0 10 10 0 0 % T
% Val: 0 0 0 20 0 10 0 0 0 0 10 0 0 10 0 % V
% Trp: 20 60 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 50 30 70 10 10 10 60 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _