KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTBS
All Species:
28.18
Human Site:
Y237
Identified Species:
56.36
UniProt:
Q01459
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01459
NP_004379.1
385
43760
Y237
T
L
T
G
Y
N
D
Y
I
K
M
S
I
N
P
Chimpanzee
Pan troglodytes
XP_513520
382
43414
Y234
T
L
T
G
Y
N
D
Y
I
K
M
S
I
N
P
Rhesus Macaque
Macaca mulatta
XP_001107057
382
43388
Y234
T
L
T
G
Y
N
D
Y
I
K
M
S
I
N
P
Dog
Lupus familis
XP_547309
379
42974
Y234
T
L
T
G
Y
D
D
Y
I
K
I
G
I
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R242
366
41277
Y221
T
L
T
G
Y
I
D
Y
I
K
M
G
I
S
P
Rat
Rattus norvegicus
Q01460
367
41513
Y222
T
L
T
G
Y
G
D
Y
L
R
M
G
I
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514959
321
36574
R180
L
G
Y
E
D
Y
I
R
M
G
I
S
P
K
K
Chicken
Gallus gallus
XP_422372
364
40668
Y221
T
L
F
G
Y
E
E
Y
I
T
M
G
I
D
P
Frog
Xenopus laevis
NP_001079731
370
41631
F224
T
I
S
G
Y
E
K
F
I
Q
L
G
I
E
P
Zebra Danio
Brachydanio rerio
NP_001018565
361
40932
Y217
T
L
T
A
Y
D
Q
Y
I
S
M
N
I
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W092
484
54104
L267
K
F
S
I
D
Y
L
L
K
L
G
A
P
P
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798621
421
47990
K229
Q
G
V
D
D
F
I
K
A
G
V
P
P
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
94.2
76.6
N.A.
80.2
77.1
N.A.
64.4
69.6
60
63.6
N.A.
21.6
N.A.
N.A.
28.5
Protein Similarity:
100
98.4
96.6
83.1
N.A.
86.7
86.2
N.A.
74.5
79.4
74.2
76.3
N.A.
38.2
N.A.
N.A.
45.8
P-Site Identity:
100
100
100
80
N.A.
80
66.6
N.A.
6.6
60
40
60
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
20
73.3
73.3
80
N.A.
13.3
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
9
0
0
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
25
17
50
0
0
0
0
0
0
17
0
% D
% Glu:
0
0
0
9
0
17
9
0
0
0
0
0
0
9
9
% E
% Phe:
0
9
9
0
0
9
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
17
0
67
0
9
0
0
0
17
9
42
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
9
0
9
17
0
67
0
17
0
75
0
0
% I
% Lys:
9
0
0
0
0
0
9
9
9
42
0
0
0
9
17
% K
% Leu:
9
67
0
0
0
0
9
9
9
9
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
59
0
0
0
0
% M
% Asn:
0
0
0
0
0
25
0
0
0
0
0
9
0
34
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
9
25
9
75
% P
% Gln:
9
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% R
% Ser:
0
0
17
0
0
0
0
0
0
9
0
34
0
17
0
% S
% Thr:
75
0
59
0
0
0
0
0
0
9
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
75
17
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _