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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTBS
All Species:
16.67
Human Site:
Y346
Identified Species:
33.33
UniProt:
Q01459
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01459
NP_004379.1
385
43760
Y346
K
A
T
Y
I
Q
N
Y
R
L
R
G
I
G
M
Chimpanzee
Pan troglodytes
XP_513520
382
43414
Y343
K
A
T
Y
I
Q
N
Y
R
L
R
G
I
G
M
Rhesus Macaque
Macaca mulatta
XP_001107057
382
43388
Y343
K
A
T
Y
I
Q
N
Y
G
L
R
G
I
G
M
Dog
Lupus familis
XP_547309
379
42974
H343
K
A
A
Y
I
Q
K
H
G
L
R
G
I
G
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8R242
366
41277
Y330
K
A
A
Y
V
K
N
Y
G
L
R
G
I
G
M
Rat
Rattus norvegicus
Q01460
367
41513
Y331
K
A
A
F
V
K
H
Y
G
L
R
G
I
G
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514959
321
36574
L289
A
Y
A
R
D
R
G
L
R
G
I
G
M
W
N
Chicken
Gallus gallus
XP_422372
364
40668
R330
K
A
A
Y
V
K
N
R
G
L
K
G
I
G
M
Frog
Xenopus laevis
NP_001079731
370
41631
H333
K
S
A
Y
V
K
I
H
G
L
R
G
I
G
M
Zebra Danio
Brachydanio rerio
NP_001018565
361
40932
H326
K
A
A
Y
V
M
Q
H
G
L
K
G
I
G
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W092
484
54104
K376
K
V
L
F
A
M
S
K
R
L
A
G
V
M
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798621
421
47990
A338
Y
G
V
S
V
Y
Q
A
D
C
L
D
Y
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
94.2
76.6
N.A.
80.2
77.1
N.A.
64.4
69.6
60
63.6
N.A.
21.6
N.A.
N.A.
28.5
Protein Similarity:
100
98.4
96.6
83.1
N.A.
86.7
86.2
N.A.
74.5
79.4
74.2
76.3
N.A.
38.2
N.A.
N.A.
45.8
P-Site Identity:
100
100
93.3
73.3
N.A.
73.3
60
N.A.
13.3
60
53.3
53.3
N.A.
26.6
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
80
N.A.
86.6
86.6
N.A.
26.6
80
80
73.3
N.A.
53.3
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
67
59
0
9
0
0
9
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
9
0
0
9
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
9
0
59
9
0
92
0
75
0
% G
% His:
0
0
0
0
0
0
9
25
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
34
0
9
0
0
0
9
0
75
0
0
% I
% Lys:
84
0
0
0
0
34
9
9
0
0
17
0
0
0
0
% K
% Leu:
0
0
9
0
0
0
0
9
0
84
9
0
0
0
0
% L
% Met:
0
0
0
0
0
17
0
0
0
0
0
0
9
9
75
% M
% Asn:
0
0
0
0
0
0
42
0
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
34
17
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
9
0
9
34
0
59
0
0
0
0
% R
% Ser:
0
9
0
9
0
0
9
0
0
0
0
0
0
9
0
% S
% Thr:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
9
% T
% Val:
0
9
9
0
50
0
0
0
0
0
0
0
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
9
9
0
67
0
9
0
42
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _