Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CAP1 All Species: 37.27
Human Site: Y172 Identified Species: 82
UniProt: Q01518 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q01518 NP_001099000.1 475 51855 Y172 T N R V L K E Y K D V D K K H
Chimpanzee Pan troglodytes XP_001172088 456 49484 E171 Y T N R V L K E Y K D V D K K
Rhesus Macaque Macaca mulatta XP_001082428 474 51510 Y171 T N R V L K E Y K D V D K K H
Dog Lupus familis XP_848565 475 51435 Y172 T N R V L K E Y K D V D K K H
Cat Felis silvestris
Mouse Mus musculus P40124 474 51556 Y171 T N R V L K E Y R D V D K K H
Rat Rattus norvegicus Q08163 474 51570 Y171 T N R V L K E Y R D V D K K H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508035 478 53360 Y178 T N R V L K D Y K H S D L R H
Chicken Gallus gallus XP_418936 480 53179 Y175 T N R V L K D Y K H S D T R H
Frog Xenopus laevis NP_001082639 476 51360 Y166 T N R V L K E Y K D V D K K H
Zebra Danio Brachydanio rerio NP_956203 463 49378 Y169 T N R V L K D Y K E K D K T H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P17555 526 57503 Y207 T N R I L K E Y R E S D P N A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.8 97.6 94.7 N.A. 94.1 94.5 N.A. 64.4 65.2 71.4 64.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 94.9 98.5 96.2 N.A. 96.6 96.8 N.A. 77.4 77.9 83.4 77 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 100 N.A. 93.3 93.3 N.A. 66.6 66.6 100 73.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. 80 80 100 86.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 35.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 53.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 28 0 0 55 10 91 10 0 0 % D
% Glu: 0 0 0 0 0 0 64 10 0 19 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 82 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 91 10 0 64 10 10 0 64 64 10 % K
% Leu: 0 0 0 0 91 10 0 0 0 0 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 91 10 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 91 10 0 0 0 0 28 0 0 0 0 19 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 28 0 0 0 0 % S
% Thr: 91 10 0 0 0 0 0 0 0 0 0 0 10 10 0 % T
% Val: 0 0 0 82 10 0 0 0 0 0 55 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 91 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _