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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FLI1 All Species: 23.03
Human Site: S406 Identified Species: 50.67
UniProt: Q01543 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q01543 NP_002008.2 452 50982 S406 N F V P P H P S S M P V T S S
Chimpanzee Pan troglodytes XP_508856 453 51050 S407 N F V P P H P S S M P V T S S
Rhesus Macaque Macaca mulatta XP_001082387 455 51242 P409 Q K M N F V A P H P P A L P V
Dog Lupus familis XP_546404 451 50812 T405 N F V P P H P T S M P V T S S
Cat Felis silvestris
Mouse Mus musculus P26323 452 50983 S406 N F V P S H P S S M P V T S S
Rat Rattus norvegicus NP_001017381 452 50948 S406 N F V Q P H P S S M P V T S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509996 570 64208 P524 Q K M N F V P P H P P A L P V
Chicken Gallus gallus Q90837 478 53895 S406 Q P H P P E S S M Y K Y P S D
Frog Xenopus laevis P41157 453 50997 S407 N F V P S H P S S M P V T S S
Zebra Danio Brachydanio rerio A3FEM2 235 26324 G190 S G F S Y W P G S P P T L Y H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P29774 490 52037 M441 F M S P H H G M T S S S A S I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 67.4 97.3 N.A. 96.6 96.2 N.A. 53.6 64.6 83.2 29.4 N.A. 36.9 N.A. N.A. N.A.
Protein Similarity: 100 99.5 77.8 98.2 N.A. 98.4 98.4 N.A. 62.9 75.3 92.4 37.8 N.A. 49.3 N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 93.3 N.A. 93.3 93.3 N.A. 13.3 26.6 93.3 20 N.A. 20 N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 100 N.A. 93.3 93.3 N.A. 20 26.6 93.3 26.6 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 0 0 0 19 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 55 10 0 19 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 10 10 0 0 0 0 0 0 0 % G
% His: 0 0 10 0 10 64 0 0 19 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 0 19 0 0 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 28 0 0 % L
% Met: 0 10 19 0 0 0 0 10 10 55 0 0 0 0 0 % M
% Asn: 55 0 0 19 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 0 64 46 0 73 19 0 28 82 0 10 19 0 % P
% Gln: 28 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 10 10 19 0 10 55 64 10 10 10 0 73 55 % S
% Thr: 0 0 0 0 0 0 0 10 10 0 0 10 55 0 0 % T
% Val: 0 0 55 0 0 19 0 0 0 0 0 55 0 0 19 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 10 0 10 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _