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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC7A5
All Species:
22.73
Human Site:
S225
Identified Species:
50
UniProt:
Q01650
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01650
NP_003477.4
507
55010
S225
Q
I
G
K
G
D
V
S
N
L
D
P
N
F
S
Chimpanzee
Pan troglodytes
XP_001157788
507
55036
S225
Q
I
G
K
G
D
V
S
N
L
D
P
K
F
S
Rhesus Macaque
Macaca mulatta
XP_001087337
348
36825
E105
V
G
A
L
C
Y
A
E
L
G
T
T
I
S
K
Dog
Lupus familis
XP_850176
461
50529
S179
Q
I
G
K
G
D
V
S
N
L
D
P
K
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z127
512
55884
S230
D
M
G
Q
G
D
A
S
N
L
Q
Q
K
L
S
Rat
Rattus norvegicus
Q63016
512
55885
S230
D
I
G
Q
G
D
A
S
N
L
H
Q
K
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508934
507
55257
S225
Q
L
G
K
G
N
V
S
N
L
N
P
E
F
S
Chicken
Gallus gallus
NP_001025750
526
56393
T244
Q
I
A
T
G
D
V
T
S
L
T
P
E
H
S
Frog
Xenopus laevis
A1L3M3
510
55983
Q213
I
V
K
L
S
Q
G
Q
T
E
N
F
E
D
S
Zebra Danio
Brachydanio rerio
Q59I64
468
51216
F180
I
V
K
L
C
Q
G
F
T
I
N
F
E
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50276
574
63203
S238
G
L
K
D
G
Y
Q
S
H
N
F
R
N
A
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
66.8
87.3
N.A.
91
91.4
N.A.
87.5
81.5
47.8
48.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
67.4
89.3
N.A.
94.7
94.9
N.A.
92.6
88.4
67.6
65.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
0
93.3
N.A.
46.6
53.3
N.A.
73.3
53.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
0
93.3
N.A.
60
60
N.A.
93.3
66.6
20
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
0
0
28
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
0
0
10
0
55
0
0
0
0
28
0
0
19
0
% D
% Glu:
0
0
0
0
0
0
0
10
0
10
0
0
37
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
10
19
0
37
10
% F
% Gly:
10
10
55
0
73
0
19
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
10
0
0
10
0
% H
% Ile:
19
46
0
0
0
0
0
0
0
10
0
0
10
0
0
% I
% Lys:
0
0
28
37
0
0
0
0
0
0
0
0
37
0
10
% K
% Leu:
0
19
0
28
0
0
0
0
10
64
0
0
0
19
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
55
10
28
0
19
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
46
0
0
0
% P
% Gln:
46
0
0
19
0
19
10
10
0
0
10
19
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
0
0
0
0
10
0
0
64
10
0
0
0
0
10
82
% S
% Thr:
0
0
0
10
0
0
0
10
19
0
19
10
0
0
0
% T
% Val:
10
19
0
0
0
0
46
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _