KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TFAP4
All Species:
9.39
Human Site:
S178
Identified Species:
25.83
UniProt:
Q01664
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01664
NP_003214.1
338
38726
S178
M
L
E
E
Q
V
R
S
L
E
A
H
M
Y
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095929
240
26760
S109
K
R
F
I
Q
E
L
S
G
S
S
P
K
R
R
Dog
Lupus familis
XP_547149
337
38541
S178
M
L
E
E
Q
V
R
S
L
E
A
H
M
Y
P
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521575
249
28272
Q118
T
Q
L
K
R
F
I
Q
E
L
S
G
S
S
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_476605
631
67145
M279
L
L
E
D
E
L
Q
M
I
K
R
Q
L
Y
S
Honey Bee
Apis mellifera
XP_001122450
537
59082
V253
R
L
E
K
Q
M
R
V
I
Q
N
Q
L
Y
P
Nematode Worm
Caenorhab. elegans
P34474
431
46089
L281
T
T
S
T
P
L
S
L
L
T
L
N
G
S
P
Sea Urchin
Strong. purpuratus
XP_783888
389
44597
S199
V
V
E
E
R
N
R
S
L
E
S
Q
L
Y
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LEZ3
529
58692
K309
L
I
P
N
S
D
Q
K
R
D
K
A
S
F
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
62.1
97
N.A.
N.A.
N.A.
N.A.
59.1
N.A.
N.A.
N.A.
N.A.
24
28.4
23.2
34.1
Protein Similarity:
100
N.A.
64.7
97.9
N.A.
N.A.
N.A.
N.A.
64.1
N.A.
N.A.
N.A.
N.A.
35.6
43.2
38.9
51.6
P-Site Identity:
100
N.A.
13.3
100
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
20
40
13.3
53.3
P-Site Similarity:
100
N.A.
20
100
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
73.3
73.3
26.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
23
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
0
12
0
0
0
12
0
0
0
0
0
% D
% Glu:
0
0
56
34
12
12
0
0
12
34
0
0
0
0
0
% E
% Phe:
0
0
12
0
0
12
0
0
0
0
0
0
0
12
0
% F
% Gly:
0
0
0
0
0
0
0
0
12
0
0
12
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
23
0
0
0
% H
% Ile:
0
12
0
12
0
0
12
0
23
0
0
0
0
0
0
% I
% Lys:
12
0
0
23
0
0
0
12
0
12
12
0
12
0
0
% K
% Leu:
23
45
12
0
0
23
12
12
45
12
12
0
34
0
12
% L
% Met:
23
0
0
0
0
12
0
12
0
0
0
0
23
0
0
% M
% Asn:
0
0
0
12
0
12
0
0
0
0
12
12
0
0
0
% N
% Pro:
0
0
12
0
12
0
0
0
0
0
0
12
0
0
67
% P
% Gln:
0
12
0
0
45
0
23
12
0
12
0
34
0
0
0
% Q
% Arg:
12
12
0
0
23
0
45
0
12
0
12
0
0
12
12
% R
% Ser:
0
0
12
0
12
0
12
45
0
12
34
0
23
23
12
% S
% Thr:
23
12
0
12
0
0
0
0
0
12
0
0
0
0
0
% T
% Val:
12
12
0
0
0
23
0
12
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
56
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _