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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CACNA1D All Species: 12.73
Human Site: T2105 Identified Species: 40
UniProt: Q01668 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q01668 NP_000711.1 2161 245141 T2105 E M E S A A S T L L N G N V R
Chimpanzee Pan troglodytes XP_516530 2159 244803 T2103 E M E S A A S T L L N G N V H
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_858663 2161 244601 N2105 E M E S A A S N L L N G T V H
Cat Felis silvestris
Mouse Mus musculus Q99246 2179 246987 T2123 E M E S A A S T L L N G S V C
Rat Rattus norvegicus P27732 2203 250118 T2147 E M E S A A S T L L N G S V C
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus O73700 2190 249326 N2134 E M E S A A S N L L N G N I S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_982351 2082 237054 H2022 E M E S A A S H X L N G G I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24270 2516 276682 N2469 V T T T N N N N K S Q V S Q N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.4 N.A. 97.2 N.A. 95.9 94.3 N.A. N.A. 86.6 N.A. 75.5 N.A. 44.4 N.A. N.A. N.A.
Protein Similarity: 100 98 N.A. 98 N.A. 97.6 96.1 N.A. N.A. 91.8 N.A. 83.1 N.A. 57 N.A. N.A. N.A.
P-Site Identity: 100 93.3 N.A. 80 N.A. 86.6 86.6 N.A. N.A. 80 N.A. 66.6 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 93.3 N.A. 80 N.A. 93.3 93.3 N.A. N.A. 86.6 N.A. 73.3 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 88 88 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 88 0 88 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 88 13 0 0 % G
% His: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 25 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 25 0 % I
% Lys: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 75 88 0 0 0 0 0 % L
% Met: 0 88 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 13 13 13 38 0 0 88 0 38 0 13 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 13 0 0 13 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % R
% Ser: 0 0 0 88 0 0 88 0 0 13 0 0 38 0 13 % S
% Thr: 0 13 13 13 0 0 0 50 0 0 0 0 13 0 13 % T
% Val: 13 0 0 0 0 0 0 0 0 0 0 13 0 63 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _