KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1D
All Species:
18.79
Human Site:
Y1865
Identified Species:
59.05
UniProt:
Q01668
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01668
NP_000711.1
2161
245141
Y1865
P
T
W
S
R
Q
N
Y
G
Y
Y
S
R
Y
P
Chimpanzee
Pan troglodytes
XP_516530
2159
244803
Y1863
P
T
W
S
R
Q
N
Y
G
Y
Y
S
R
Y
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_858663
2161
244601
Y1865
P
A
G
G
R
Q
S
Y
N
Y
Y
N
R
Y
P
Cat
Felis silvestris
Mouse
Mus musculus
Q99246
2179
246987
Y1883
P
T
W
S
R
Q
N
Y
N
Y
Y
N
R
Y
P
Rat
Rattus norvegicus
P27732
2203
250118
Y1907
P
T
W
S
R
Q
N
Y
S
Y
Y
N
R
Y
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
Y1894
L
S
G
N
R
H
V
Y
D
Y
H
C
R
H
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_982351
2082
237054
D1786
G
E
E
F
Y
E
D
D
S
M
L
S
G
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24270
2516
276682
Q2233
L
A
A
A
G
K
L
Q
D
E
L
Q
G
A
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
N.A.
97.2
N.A.
95.9
94.3
N.A.
N.A.
86.6
N.A.
75.5
N.A.
44.4
N.A.
N.A.
N.A.
Protein Similarity:
100
98
N.A.
98
N.A.
97.6
96.1
N.A.
N.A.
91.8
N.A.
83.1
N.A.
57
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
60
N.A.
86.6
86.6
N.A.
N.A.
26.6
N.A.
6.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
73.3
N.A.
93.3
93.3
N.A.
N.A.
53.3
N.A.
20
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
25
13
13
0
0
0
0
0
0
0
0
0
13
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% C
% Asp:
0
0
0
0
0
0
13
13
25
0
0
0
0
13
0
% D
% Glu:
0
13
13
0
0
13
0
0
0
13
0
0
0
0
0
% E
% Phe:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
0
25
13
13
0
0
0
25
0
0
0
25
0
13
% G
% His:
0
0
0
0
0
13
0
0
0
0
13
0
0
13
13
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% K
% Leu:
25
0
0
0
0
0
13
0
0
0
25
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% M
% Asn:
0
0
0
13
0
0
50
0
25
0
0
38
0
0
0
% N
% Pro:
63
0
0
0
0
0
0
0
0
0
0
0
0
0
63
% P
% Gln:
0
0
0
0
0
63
0
13
0
0
0
13
0
0
0
% Q
% Arg:
0
0
0
0
75
0
0
0
0
0
0
0
75
0
13
% R
% Ser:
0
13
0
50
0
0
13
0
25
0
0
38
0
0
0
% S
% Thr:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
13
0
0
75
0
75
63
0
0
63
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _